Supportive medication in cancer during pregnancy

Abstract

While pregnancy-related malignancies are quite rare, their incidence is increasing and thus affecting more and more women nowadays. Their management, however, with both chemotherapy and supportive agents remains quite challenging and it seems crucial to define the optimal treatment for this special population. Concerning supportive medication, it is clinically significant to determine whether commonly used agents, including Granulocyte Colony-Stimulating Factors, Erythropoiesis-stimulating agents, Bisphosphonates, Anticoagulation agents, Antiemetics and Glucocorticoids are indeed effective in ameliorating chemotherapy side effects. Meanwhile, it is of great importance that the administration of any of these agents is safe for both mother and fetus. This review aims to provide a précis of the current literature regarding both safety and efficacy of all categories of supportive medication during pregnancy.

Pregnancy Associated with Breast Cancer: a review of the literature

“…The appearance on US is a low echogenic mass with irregular edges attached to a liquid, which presents central necrosis or cystic degeneration, due to the blood demand for tumor growth (30). If accompanied by microcalcifications, it may indicate breast cancer, unlike macrocalcifications, which are physiological (36,37,38). Combined with mammography, it generates an increase of 15.5% in the MRI screening rate for ipsilateral cancer and 3.9% for contralateral cancer.…”