Suppression of allergic and inflammatory responses by essential oils derived from herbal plants and citrus fruits

Mitoshi, Mai; Kuriyama, Isoko; Nakayama, Hiromichi; Miyazato, Hironari; Sugimoto, Keiichiro; Kobayashi, Yuko; Jippo, Tomoko; Kuramochi, Kouji; Yoshida, Hiromi; Mizushina, Yoshiyuki

doi:10.3892/ijmm.2014.1720

Cited by 35 publications

(18 citation statements)

References 32 publications

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“…28 a-Terpineol suppresses the production of inammatory mediators in LPS-stimulated human macrophages by regulating NF-kB and MAPKs. 28 Moreover, borneol exhibits remarkable anti-inammatory effects by reducing the level of inammatory factors in the LPS-induced RAW264.7 macrophages. 29 These reports suggest that the complexes of these compounds in XQEO contribute to the anti-inammatory properties of XQEO.…”

Section: Discussionmentioning

confidence: 99%

Xiao Qing Long Tang essential oil exhibits inhibitory effects on the release of pro-inflammatory mediators by suppressing NF-κB, AP-1, and IRF3 signalling in the lipopolysaccharide-stimulated RAW264.7 cells

et al. 2019

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Section: Discussionmentioning

confidence: 99%

Xiao Qing Long Tang essential oil exhibits inhibitory effects on the release of pro-inflammatory mediators by suppressing NF-κB, AP-1, and IRF3 signalling in the lipopolysaccharide-stimulated RAW264.7 cells

et al. 2019

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“…The elucidation of the pharmacological functions of lemongrass EO in vivo may provide a rationale for the clinical application of this EO as an anti-allergic and anti-inflammatory substance. [4] The muscle spasms being very common among the people, this study was done to find the effect of lemon grass oil on the same. The present study reveals that the pain levels of the patient has got gradually decreased during the application of lemongrass oil.…”

Section: Discussionmentioning

confidence: 99%

Effect of Lemongrass Oil on Rheumatoid Arthritis

M¹,

Devi²

2017

Int j curr adv res

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Aim:To do a research on the effect of lemongrass oil on muscle spasms. Methods:A total of 30 participants who were suffering from muscle spasms were chosen. They were given lemongrass oil to apply for about 30 days. The pain scale was noted once in five days. Results:The result showed a moderate changes in the pain levels of the patient. Further application would significantly show a greater decrease in the pain levels of the patient. Conclusion:Muscle spasms being more common in old people, this study was conducted to create awareness about the effect of lemongrass oil on the same. INTRODUCTIONLemongrass (Cymbopogon) is a tall perennial plant from the Graminieae family, which thrives in tropical and subtropical regions.Lemongrass oil is extracted through the process of steam distillation from the dried leaves of the plant. It has a thin consistency, and a pale or bright yellow color. It has a strong, fresh, lemony, and earthy scent. Lemongrass oil can help relax and tone the muscles, as well as relieve muscle pain, rheumatism.The main compounds of lemongrass oil are geranyl acetate, myrcene, nerol, citronellal, terpineol, methyl heptenone, dipentene, geraniol, neral, farnesol, limonene, and citral. Another beneficial compound in lemongrass is limonene, which helps reduce inflammation and kill bacteria, according to research. According to a 2005 study by Dr. Sue Chao, lemongrass oil is one of the top six essential oils with antiinflammatory properties. [1] Muscle spasms are involuntary, generally painful contractions of a muscle or muscle group, [12] When the motor system is stressed,either by a neuromuscular disease or by a physiologic stress such as dehydration or excessive exercise,cramps become more frequent. Muscle cramps are caused by ectopic discharges from nerves or nerve terminals. [13] Cramps are also frequent during the last trimester of pregnancy and in athletes such as marathon runners Aromatic and medicinal plants are still a major part of traditional medicine in the developing countries. MATERIALS AND METHODSThe pure essential lemongrass oil was commercially bought. A total of 30 patients suffering from muscle spasms were chosen. They belonged to different age groups varying from 35 to 60. They were given lemongrass oil of about 3ml for each person and asked to apply for about 30 days. The people applying oil occasionally for muscle spasms are asked to stop that while applying the lemon grass oil. The pain scale was noted once in 5 days. The pain scale considered in this study was from 1-6, 1 being the lowest or no pain and 6 being the severe pain. A table was prepared for the days and the pain scale noted. Accordingly a graph was also drawn. International Journal of Current Advanced Research A R T I C L E I N F O A B S T R A C T Aim:To do a research on the effect of lemongrass oil on muscle spasms.Methods: A total of 30 participants who were suffering from muscle spasms were chosen. They were given lemongrass oil to apply for about 30 days. The pain scale was noted once in five days. Results:Th...

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“…Various species of Citrus have been used as foods, and their fruits, leaves, and roots have also been used as folk medicine or spice in Taiwan [ 1 ]. Citrus is one genus of the economically and medicinally important Rutaceae family, which has shown extensive biological and pharmacological activities, including antitumor [ 2 , 3 , 4 , 5 , 6 , 7 ], antiallergic [ 8 ], antioxidant [ 9 , 10 , 11 , 12 ], antiplatelet aggregation [ 13 ], anti-microbial [ 14 , 15 , 16 , 17 ], and anti-inflammatory activity [ 18 , 19 , 20 , 21 , 22 ]. Moreover, Citrus species have been reported to contain various bioactive coumarins, flavonoids, tetranortriterpenoids, monoterpenoids, and acridone alkaloids [ 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ].…”

Section: Introductionmentioning

confidence: 99%

Constituents of the Fruits of Citrus medica L. var. sarcodactylis and the Effect of 6,7-Dimethoxy-coumarin on Superoxide Anion Formation and Elastase Release

et al. 2017

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Investigation of the chemical constituents from the fruits of Citrus medica L. var. sarcodactylis Swingle has led to the characterization of a new sesquiterpene 1 along with thirty-two known compounds. The structure of 1 was established on the basis of 2D NMR spectroscopic and mass spectrometric analyses, and the known compounds were identified by comparison of their physical and spectroscopic data with those reported in the literature. In addition, most of the isolated compounds were evaluated for the activity assayed by the in vitro inhibition of superoxide anion generation and elastase release by human neutrophils. The results showed that only 6,7-dimethoxycoumarin (5) exhibited significant inhibition of superoxide anion generation, with IC50 value of 3.8 ± 1.4 μM.

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Suppression of allergic and inflammatory responses by essential oils derived from herbal plants and citrus fruits

Cited by 35 publications

References 32 publications

Xiao Qing Long Tang essential oil exhibits inhibitory effects on the release of pro-inflammatory mediators by suppressing NF-κB, AP-1, and IRF3 signalling in the lipopolysaccharide-stimulated RAW264.7 cells

Xiao Qing Long Tang essential oil exhibits inhibitory effects on the release of pro-inflammatory mediators by suppressing NF-κB, AP-1, and IRF3 signalling in the lipopolysaccharide-stimulated RAW264.7 cells

Effect of Lemongrass Oil on Rheumatoid Arthritis

Constituents of the Fruits of Citrus medica L. var. sarcodactylis and the Effect of 6,7-Dimethoxy-coumarin on Superoxide Anion Formation and Elastase Release

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