Studies of single-event laser-target interaction for fusion reaction schemes leading to volume ignition are discussed. Conditions were explored where single-event ns-laser pulses give rise to temperatures sufficient for volume ignition. Thus, ignition is possible, particularly if X-ray reabsorption is sufficiently high. Unfortunately, this scheme requires laser pulses with energies above 5 MJ and target densities of compressed DT above 1000 g/cm−3. Both requirements are quite demanding for near term systems. Nevertheless the present state technology and the detailed knowledge about volume ignition at direct drive are a basis. Systems as NIF or LMJ can well confirm these physics-clarified conditions and the technology for large laser systems with sufficient repetition rate and for a drastic reduction of the size and costs is necessary and possible and by physics similar to the known reductions in transistor development.