Suppression of preadipocyte determination by SOX4 limits white adipocyte hyperplasia in obesity

M2 macrophage-derived TGF-β induces age-associated loss of adipogenesis through progenitor cell senescence

“…2G ). Gene regulatory network inference revealed that p16 high cells had low proliferative capacity (low Myc, Junb, and Fosl1) [ 43 ], and adipose differentiation potential (Cebpb and Sox4) [ 44 , 45 ] ( Figure 1 G).…”