Supracondylar femur fracture repair using IlluminOss in a patient with Osteogenesis Imperfecta type 4

Meijering, Daniëlle; Harsevoort, Gerrit Jan; Janus, A. J. M.; Helden, Sven H. van

doi:10.1016/j.jor.2018.05.045

Cited by 8 publications

(5 citation statements)

References 3 publications

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“…In select cases with particularly large lesions two implants were used for augmented space filling in a manner previously shown to be effective in the distal femoral metaphysis (Figure 3C), 11,12 reaming up to 8 mm and using a 9 mm implant. We have also augmented our constructs with a second S1 implant or a supplemental PDN across the S2 corridor, which can be performed in the same manner 11 and still permits reaming up to 8 mm for a 9 mm implant (Figure 3C).…”

Section: Surgical Techniquementioning

confidence: 99%

How I do it: Percutaneous stabilization of symptomatic sacral and periacetabular metastatic lesions with photodynamic nails

Fourman

Ramsey

Newman

et al. 2021

Journal of Surgical Oncology

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Section: Surgical Techniquementioning

confidence: 99%

How I do it: Percutaneous stabilization of symptomatic sacral and periacetabular metastatic lesions with photodynamic nails

Fourman

Ramsey

Newman

et al. 2021

Journal of Surgical Oncology

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“…One Level III [ 9 ], Eight Level IV [ 1 , 2 , 5 – 7 , 12 – 14 ], and three Level V [ 8 , 15 , 16 ] studies reported complications following PBSS. A total of sixty complications were reported (Table 3 ).…”

Section: Resultsmentioning

confidence: 99%

“…Similarly, two studies [ 1 , 14 ] found 96% fracture healing among pelvic and humerus fractures, respectively. One study [ 16 ] reported evidence of fracture displacement on an individual with osteogenesis imperfecta type 4. Lastly, one study reported adequate treatment of a pathologic humerus fracture in a patient with metastatic renal cancer.…”

Section: Resultsmentioning

confidence: 99%

“…Additionally, limb shortening was absent or < 5 mm for 88% (22 of 25) of fractures with 12 months of follow-up • Recurvatum/procurvatum deformity was absent in 80% (20 of 25) for fractures with 12 months of follow-up. There was no radiographic evidence of implant migration • Healing outcomes were excellent, with substantial cortical bridging and complete healing at 12 months, and total dissolution (100%) of the fracture line at the 3-month follow-up Meijering et al [ 16 ] Femur • Fracture fragments dislocated. Consolidation present at 6 months Oikonomidis et al [ 14 ] Pelvis • Consolidated pubis ramus fractures were reported in 96% of the cases at 6 months Surke et al [ 12 ] Fifth metacarpal • At a median follow-up of 13 weeks, all fractures had radiologically healed, and there were no instances of delayed union or non-union.…”

Section: Resultsmentioning

confidence: 99%

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Photodynamic bone stabilization for traumatic and pathologic fractures: a systematic review of utilization, complications, and patient-reported outcomes

Zhu,

McNassor,

Hecht II

et al. 2024

Eur J Orthop Surg Traumatol

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Introduction The photodynamic bone stabilization system (PBSS) was was developed in 2010, and in 2018 gained FDA approval in the United States. Given its relative novelty, our analysis sought to analyze the available literature exploring the indications, outcomes, and complications of the PBSS. Methods We performed a systematic review (PROSPERO registration of study protocol: CRD42022363065, October 8th, 2022). PubMed, EBSCOHost, and Google Scholar electronic databases were queried to identify articles evaluating PBSS in the treatment of pathologic or traumatic fractures between January 1 2010 and 15 October 2022. The quality of the included studies was assessed using the Methodological Index for Nonrandomized Studies tool. Results Our initial search yielded 326 publications, which were then screened for appropriate studies that aligned with the purpose of our review. A total of thirteen studies, comprising seven case series, four case reports, and two cohort studies. The total sample size of the included studies consisted of 345 patients, with 242 females (70%) and 103 males (30%). The implants were most commonly utilized in the humerus (41%), radius (12%), and metacarpal (12%). The most common complications were related to broken implants (5%) and dislocation (1%). Most studies reported complete fracture healing and return of full strength and range of motion. Conclusion Despite being a relatively novel technology, PBSS appears to be a viable option for fracture stabilization. Most studies included in our analysis reported complete fracture healing and return of function with minimal complications.

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“…No significant differences were registered in reoperation rates, but the rate of broken implants was significantly higher in patients treated with a polymeric rod [ 27 ]. Although the photodynamic polymer stabilization system is usually indicated for metastatic and osteoporotic fractures of non-weight-bearing bones fractures, several other uses are reported in the literature such as compassionate stabilization of femoral fractures in nonambulant patients [ 23 ] and surgical augmentation of acetabular and femoral fractures in patients with osteogenesis imperfecta [ 28 , 29 ]. Also, a preliminary study on sheep provided encouraging results in the treatment of weight-bearing bone fractures [ 30 ].…”

Section: Discussionmentioning

confidence: 99%

Electrochemotherapy and Simultaneous Photodynamic Bone Stabilization of Upper Limbs in Metastatic Renal Cancer Disease: Case Report and Literature Review

Albertini

Conti

Ratto

et al. 2020

Case Reports in Medicine

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Introduction. Metastatic bone disease represents a systemic pathology that heavily affects the quality of life of oncologic patients causing pain and functional disability. Methodology. We present the case of a patient with a history of renal cell cancer presenting pathologic fractures of both humeri and proximal right radius. Results. After a careful multidisciplinary approach, an adjuvant anticancer therapy and a photodynamic bone stabilization procedure were performed with a minimally invasive technique aiming to minimize pain and local disease progression, while restoring functional autonomy and improving the patient’s quality of life. Electrochemotherapy was delivered on the lytic bone lesions with extraskeletal involvement of the proximal left humerus and the proximal right radius, and then polymeric bone stabilization was performed on both humeri. At two months of follow-up, the patient presented satisfactory functional scores (MSTS score: 12/30 bilaterally; DASH scores: 46.7/100 for the right side and 48.3/100 for the left one), and pain was well controlled with opioid analgesics. Radiographs showed good results in terms of ossification of lytic bone lesions and durability of polymeric stabilization. At four months of follow-up, the patient reported a stable clinical scenario. Six months after surgery, due to extremely poor prognosis after the progression of primary disease, the patient was referred to palliative care and died shortly thereafter. Conclusion. Over the last decade, the management of metastatic bone disease has changed. Low-toxicity and minimally invasive procedures such as electrochemotherapy and polymeric bone stabilization might be performed concomitantly in selected patients, as an alternative to radiation therapy and to more demanding surgical procedures such as plating and adjuvant cementing.

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Supracondylar femur fracture repair using IlluminOss in a patient with Osteogenesis Imperfecta type 4

Cited by 8 publications

References 3 publications

How I do it: Percutaneous stabilization of symptomatic sacral and periacetabular metastatic lesions with photodynamic nails

How I do it: Percutaneous stabilization of symptomatic sacral and periacetabular metastatic lesions with photodynamic nails

Photodynamic bone stabilization for traumatic and pathologic fractures: a systematic review of utilization, complications, and patient-reported outcomes

Electrochemotherapy and Simultaneous Photodynamic Bone Stabilization of Upper Limbs in Metastatic Renal Cancer Disease: Case Report and Literature Review

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