Supragastric belch may be related to globus symptom – a prospective clinical study

Nevalainen, Pia; Walamies, Markku; Kruuna, Olli; Arkkila, Perttu; Aaltonen, Leena‐Maija

doi:10.1111/nmo.12764

Cited by 17 publications

(36 citation statements)

References 27 publications

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“…27 YÇM kullanılarak yapılan bazı çalışmaların sonucunda, yine globus ile ÜÖS basıncı arasında anlamlı bir ilişki bulunamamıştır. [28][29][30]…”

Section: Anormal üSt öZofageal Sfi̇nkter Fonksi̇yonuunclassified

“…11,32 Son yıllarda daha objektif bir yöntem olan YÇM'ler ile çeşitli çalışmalar yapılmış ve globus hastalarının yaklaşık yarısında özofageal motilite bozukluğu olduğu gözlenmiştir. 29 37…”

Section: öZofageal Motor Bozukluklarunclassified

“…67 Yöntemin çeşitli avantajlarına rağmen, TNE kullanımının globus tanısında etkili olmadığı bildirilmiştir. 29 pH monitörizasyon testine yönlendirilmektedir. 82 Fakat bu yöntem, asidik olmayan reflü (pH'nin 4,0 ve üzerinde olduğu) tespitinde yetersiz kalmaktadır.…”

Section: Teşhi̇sunclassified

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Globus Pharyngeus: Etiology, Diagnostics and Treatment

Gölaç¹,

Yılmaz²

2019

KBB ve BBC Dergisi

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oğaz ağrısı veya yutma güçlüğü oldukça sık görülen bir semptom olup; enfeksiyon, nöropati, somatizasyon ve tümör gibi oldukça farklı sebeplere bağlı olarak gelişebilir. Üç aydan fazla süren boğaz ağrıları ise kronik boğaz ağrısı olarak kabul edilir. Bu grupta yer alan klinik semptomlardan bir tanesi de globus farengeus (GF)'tur. Kulak burun boğaz (KBB), polikliniklerine gelen hastaların yaklaşık %4'ünde gözlenen bu semptom, özellikle orta yaş grubundaki kadınlarda erkeklere göre daha sık görülmektedir. 1,2 GF, boğazda bir yumru ya da yabancı cisim hissi ile sürekli devam eden veya aralıklı ortaya çıkan, genelde uzun süren ve tekrarlama olasılığı olan bir klinik semptomdur. Semptom, Galmiche ve ark. tarafından şikâyetlerin en az 6 ay sürmesi şartı ile boğazda sürekli veya ara sıra olan ağrısız kitle

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“…27 YÇM kullanılarak yapılan bazı çalışmaların sonucunda, yine globus ile ÜÖS basıncı arasında anlamlı bir ilişki bulunamamıştır. [28][29][30]…”

Section: Anormal üSt öZofageal Sfi̇nkter Fonksi̇yonuunclassified

Section: öZofageal Motor Bozukluklarunclassified

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Globus Pharyngeus: Etiology, Diagnostics and Treatment

Gölaç¹,

Yılmaz²

2019

KBB ve BBC Dergisi

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“…The etiology of globus is controversial, but presumably it has various causes. However, it has been recently shown, that gastroesophageal reflux disease (GERD) without reflux symptoms is not a cause for globus [4]. Elevated upper esophageal sphincter (UES) pressure has been suggested to play a role, but recent findings are contradictory [4,5].…”

Section: Introductionmentioning

confidence: 99%

Work-up of globus: assessing the benefits of neck ultrasound and videofluorography

Järvenpää

Ilmarinen

Geneid

et al. 2016

Eur Arch Otorhinolaryngol

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Globus patients with normal ear, nose, and throat (ENT) status are a diagnostic challenge. The symptom may be long lasting and cause concern about malignancy, leading to possibly unnecessary further investigation. The aim of the study was to assess whether radiological examinations are useful in globus diagnostics, how often patients suffer from persistent globus, and whether globus patients with normal ENT status develop a malignancy during a follow-up. We reviewed medical records of all 76 globus patients referred to Helsinki University Hospital, Department of Otorhinolaryngology-Head and Neck Surgery in 2009. Patient history and findings in physical and radiological examinations were registered. A questionnaire concerning patients' present pharyngeal symptoms was sent 3 and 6 years after their initial visit. Data from the Finnish Cancer Registry revealed whether patients developed malignancies within a 3-year follow-up. Based on medical records, neck ultrasound was performed for 37 (49 %) and videofluorography for 22 patients (29 %), with nonsignificant findings. After a 3- and 6-year follow-up, half patients indicated that they were asymptomatic or had fewer symptoms, whereas the rest had persistent symptoms. The Finnish Cancer Registry data confirmed that globus patients developed no head and neck malignancies during a 3-year follow-up. In the present study, neck ultrasound and videofluorography showed no additional benefit to evaluate the globus etiology in patients whose ENT status was normal. Half the globus patients suffered from persistent symptoms after a 3- and 6-year follow-up, indicating that globus may cause discomfort chronically. However, no patients developed malignancies during a 3-year follow-up.

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“…If a globus patient experiences long-lasting and difficult symptoms, further examinations may be required. However, these examinations should be transnasal oesophagoscopy or oesophagogastroscopy, 24-h multichannel intraluminal impedance with pH monitoring and high-resolution manometry, not barium swallow [7].…”

mentioning

confidence: 99%

Authors’ response to Commentary on “Role of barium swallow pharyngoesophagography in the management of globus pharyngeus”

Järvenpää

Arkkila

Aaltonen

2018

Eur Arch Otorhinolaryngol

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Supragastric belch may be related to globus symptom – a prospective clinical study

Abstract: Supragastric belch was more common in globus patients, suggesting the possible role of this condition in globus sensation. However, globus patients in this series had no acid or non-acid GERD or elevated UES pressure.

Cited by 17 publications

References 27 publications

Globus Pharyngeus: Etiology, Diagnostics and Treatment

Globus Pharyngeus: Etiology, Diagnostics and Treatment

Work-up of globus: assessing the benefits of neck ultrasound and videofluorography

Authors’ response to Commentary on “Role of barium swallow pharyngoesophagography in the management of globus pharyngeus”

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