Supramolecular aggregation patterns based on the bio-inspired Se(lone pair)⋯π(aryl) synthon

Supra-molecular synthons based on gold…π(arene) interactions

“…Not only do Au…Au interactions lead to fascinating supra-molecular architectures, the fact that the energy of stabilisation afforded to their crystal structures can match that provided by conventional hydrogen bonding [10] led to competition studies between these synthons [11][12][13][14]. By contrast, considerably less attention has been directed to ascertaining formation of Au…π(arene) interactions [15]; analogous interactions are well established in the supramolecular chemistry of the main group elements [16][17][18]. Herein, an overview of Au…π(arene) interactions, formed both intra-and inter-molecularly, operating in the crystal structures of molecular gold compounds is given, and their presence in macro-molecular structures is also discussed, along with future prospects for this type of interaction.…”

Supramolecular insight into the substitution of sulfur by selenium, based on crystal structures, quantum-chemical calculations and biosystem recognition

“…Non-covalent interaction has been identified as a driving force for crystal packing (Caracelli et al, 2012), self-assembly of (macro)molecules (Voth et al, 2009), stabilization of different systems (Wang et al, 2019;Breugst et al, 2017) and biological recognition (Daze & Hof, 2016). Hydrogen bonds (HBs), a class of non-covalent interaction, are generally the most abundant and the most studied.…”

14. Solute–solvent interactions mediated by main group element(lone-pair)···π(aryl) interactions

“…The element in both oxidation states has been shown to form Se(lp)···π(arene) interactions in the crystal structures of its molecular compounds [7,8]. When the accepting π-system is Compound (33), 3,4:7,8-bis(1,2-dicarba-closo-dodecaborano(1,2))-1,2,5,6-tetraselenacyclo-octane toluene solvate [51], is a zero-dimensional aggregate whereby the centrosymmetric molecule, with the eight-membered [CSe 2 C] 2 core being based on a chair, is connected to two solvent toluene molecules [d = 3.30 Å and θ = 0.5°] to form a three-molecular aggregate, as shown in Figure 14.17a.…”

“…main group element(lp)···π(arene), in the structural chemistry of main group element chemistry [2][3][4][5][6][7][8][9][10]. It is noted in passing that analogous interactions have been revealed in structural biology and are known to provide important stabilising contacts [11,12].…”

“…It is noted in passing that analogous interactions have been revealed in structural biology and are known to provide important stabilising contacts [11,12]. In molecular structural chemistry, the emphasis thus far has been upon seeking "stand-alone" element(lp)···π(arene) contacts and determining the supramolecular architectures they sustain [2][3][4][5][6][7][8][9][10]. Usually these architectures are zero-and one-dimensional; however, examples of two-and even three-dimensional aggregation patterns are known [9,10].…”