Supramolecular Chemistry in the 3rd Millennium

Abstract

The description of supramolecular chemistry as “chemistry beyond the molecule” (Jean-Marie Lehn, 1987 Nobel Lecture and Gautam R [...]

Distinct selectivity inside self-assembled coordination cages

“…Ever since its establishment, supramolecular chemistry has received enormous attention and has rapidly become one of the most important fields in modern chemistry ( Lehn, 1993 ; Lehn, 1995 ; Housecroft, 2021 ). Depending on various non-covalent interactions, supramolecular chemistry has been thoroughly studied and applied to various research areas, including molecular recognition, molecular devices, nanochemistry, and catalysis, etc.…”

Organic radical reactions confined to containers in supramolecular systems

“…Supramolecular chemistry has undergone rapid development in the past half-century, and is now an active field of modern physical organic chemistry. 5 Supramolecular phenomena are based on a wide variety of weak and reversible (non-covalent) interactions between molecules, which gives rise to molecular recognition and self-assembly processes. 6 In fact, supramolecular interactions are as old as life itself, existing in various molecular biology phenomena and activities, such as catalysis, replication, signaling and transport.…”

Site-selective reactions mediated by molecular containers

“…After decades of rapid development, supramolecular chemistry has won two times for Nobel Prizes and already became one of the most important fields in modern chemistry [13][14][15]. It is based on a wide range of noncovalent interactions between molecules [16][17][18] and has been applied to a variety of research areas including molecular recognition, molecular devices, nanochemistry, catalysis, etc.…”

“…It is based on a wide range of noncovalent interactions between molecules [16][17][18] and has been applied to a variety of research areas including molecular recognition, molecular devices, nanochemistry, catalysis, etc. [13][14][15][16][17][18]. By mimicking the recognition and catalysis behavior of enzymes with designed and synthesized molecular containers such as cyclodextrins, cucurbiturils, calixarenes, and resorcinarenes, chemists try to tackle problems of traditional synthetic chemistry, including increase in reactivity, induction of selectivity, and even emergence of new reaction pathways [19][20][21][22][23][24].…”