Supramolecular delivery of dinuclear ruthenium and osmium MCU inhibitors

Bigham, Nicholas P.; Novorolsky, Robyn J.; Davis, Keana R.; Zou, Haipei; MacMillan, Samantha N.; Stevenson, Michael J.; Robertson, George S.; Wilson, Justin J.

doi:10.1039/d4qi01102c

Inorg. Chem. Front.

2024

DOI: 10.1039/d4qi01102c

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Supramolecular delivery of dinuclear ruthenium and osmium MCU inhibitors

Nicholas P. Bigham,

Robyn J. Novorolsky,

Keana R. Davis

et al.

Abstract: The mitochondrial calcium uniporter (MCU) inhibitors Ru265 and Os245 were functionalized with adamantane to make them amenable for encapsulation in cucurbituril. The resulting host–guest complexes were investigated for their biological properties.

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Supramolecular delivery of dinuclear ruthenium and osmium MCU inhibitors

Abstract: The mitochondrial calcium uniporter (MCU) inhibitors Ru265 and Os245 were functionalized with adamantane to make them amenable for encapsulation in cucurbituril. The resulting host–guest complexes were investigated for their biological properties.

Cited by 0 publications

References 101 publications

No citations

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