Supramolecular dendrimer-containing layer-by-layer nanoassemblies for bioapplications: current status and future prospects

Abstract

Dendrimers are powerful synthetic macromolecular architectures for a wide variety of bioapplications owing to their unique and superior features, including monodispersity, well-defined and highly branched architecture, multivalency, tunable size and...

Molecular nanoarchitectonics: unification of nanotechnology and molecular/materials science

“…The current mainstream of functional material fabrication is a combination of basic technologies such as organic synthesis, self-assembly, or structure fabrication methods such as the Langmuir-Blodgett (LB) method [130,131] or layer-by-layer (LbL) assembly [132][133][134]. These conventional methodologies are now being used to create materials that can address social issues such as energy requirements [135,136], the environment [137,138], and medicine [139,140]. Many analytical studies have shown that high effectiveness and activity are due to features at the atomic and molecular level [141,142].…”

Hyperbranched Polymers: Recent Advances in Photodynamic Therapy against Cancer

“…Electrostatic interactions have been widely applied in the fabrication of nanoassemblies utilizing charged components [ 125 , 126 ]. Many first-line PDT PSs (e.g., Rose Bengal, Ce6, and protoporphyrin) are negatively charged with high singlet-oxygen generation efficiency [ 118 , 119 , 127 ].…”

“…Electrostatic interactions have been widely applied in the fabrication of nanoassemblies utilizing charged components [125,126]. Many first-line PDT PSs (e.g., Rose Bengal, Ce6, and protoporphyrin) are negatively charged with high singlet-oxygen generation As discussed in previous sections, HB polyglycerols possess good biocompatibility and long blood circulation times, and they are good candidates as PS carriers for PDT applications.…”

Functional supramolecular gels based on poly(benzyl ether) dendrons and dendrimers

“…23,24 The aforementioned unique structural properties of dendrimers make them promising candidates for potential application in biomedicine, drug delivery, diagnostics, catalysis, supramolecular materials, etc. [25][26][27][28][29][30][31] As a unique type of molecular-scale building block, dendritic molecules have been widely utilized in the construction of supramolecular gel materials in the last two decades. [32][33][34][35] In contrast to traditional LMWGs, the dendritic branching architecture ensures that there are multiple recognition sites for formation of intermolecular non-covalent interactions, which is beneficial to form robust gel-phase materials due to the multivalent effect.…”