Supramolecular prodrug vesicles for selective antimicrobial therapy employing a chemo-photodynamic strategy

Sun, Hao; Li, Shengke; Liu, Qian; Zuo, Minzan; Tian, Xueqi; Wang, Kaiya; Hu, Xiao-Yu

doi:10.1016/j.cclet.2024.109999

Chinese Chemical Letters

2024

DOI: 10.1016/j.cclet.2024.109999

|View full text |Cite

Supramolecular prodrug vesicles for selective antimicrobial therapy employing a chemo-photodynamic strategy

Hao Sun,

Shengke Li,

Qian Liu

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article3

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Photo‐Triggered ROS‐Responsive Supramolecular Nanoprodrugs for Targeted and Synergistic Chemo/Photodynamic/Gas Therapy

Shi,

Ma,

Yang

et al. 2024

Chemistry A European J

View full text Add to dashboard Cite

Photo‐triggered ROS‐responsive supramolecular nanoprodrugs (BNN6@GBTC NPs) are constructed via supramolecular self‐assembly of amphiphilic prodrug molecule (GBTC) and NO donor (BNN6). BNN6@GBTC NPs possess good stability, ROS responsiveness, and selective HepG2 cells targetability via overexpressed galactose receptors on the cell membrane. When BNN6@GBTC NPs are taken up by HepG2 cells, they can generate ROS upon light irradiation, which can not only be used for photodynamic therapy, but also cleave the thioketal linkage to release camptothecin for chemotherapy. Meanwhile, BNN6 triggering release NO for gas therapy. BNN6@GBTC NPs enable targeted and synergistic chemo/photodynamic/gas therapy, which results in reduced damage to normal cells and enhanced anti‐cancer efficacy in vitro. This work provides a novel approach for the design of nanoprodrugs based on supramolecular self‐assembly to achieve the multimodal synergistic anti‐cancer therapy.

show abstract

Photo‐Triggered ROS‐Responsive Supramolecular Nanoprodrugs for Targeted and Synergistic Chemo/Photodynamic/Gas Therapy

Shi,

Ma,

Yang

et al. 2024

Chemistry A European J

View full text Add to dashboard Cite

show abstract

A guanidiniocarbonyl-pyrrole functionalized cucurbit[7]uril derivative as a cytomembrane disruptor for synergistic antibacterial therapy

Han,

Du,

et al. 2024

J. Mater. Chem. B

View full text Add to dashboard Cite

show abstract

The Versatile Applications of Calix[4]resorcinarene-Based Cavitands

Wang,

Yan,

Liu

et al. 2024

Molecules

View full text Add to dashboard Cite

The advancement of synthetic host–guest chemistry has played a pivotal role in exploring and quantifying weak non-covalent interactions, unraveling the intricacies of molecular recognition in both chemical and biological systems. Macrocycles, particularly calix[4]resorcinarene-based cavitands, have demonstrated significant utility in receptor design, facilitating the creation of intricately organized architectures. Within the realm of macrocycles, these cavitands stand out as privileged scaffolds owing to their synthetic adaptability, excellent topological structures, and unique recognition properties. So far, extensive investigations have been conducted on various applications of calix[4]resorcinarene-based cavitands. In this review, we will elaborate on their diverse functions, including catalysis, separation and purification, polymeric materials, sensing, battery materials, as well as drug delivery. This review aims to provide a holistic understanding of the multifaceted roles of calix[4]resorcinarene-based cavitands across various applications, shedding light on their contributions to advancing the field of supramolecular chemistry.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Supramolecular prodrug vesicles for selective antimicrobial therapy employing a chemo-photodynamic strategy

Cited by 3 publications

References 27 publications

Photo‐Triggered ROS‐Responsive Supramolecular Nanoprodrugs for Targeted and Synergistic Chemo/Photodynamic/Gas Therapy

Photo‐Triggered ROS‐Responsive Supramolecular Nanoprodrugs for Targeted and Synergistic Chemo/Photodynamic/Gas Therapy

A guanidiniocarbonyl-pyrrole functionalized cucurbit[7]uril derivative as a cytomembrane disruptor for synergistic antibacterial therapy

The Versatile Applications of Calix[4]resorcinarene-Based Cavitands

Contact Info

Product

Resources

About