Supramolecular solvent-based hollow fiber liquid phase microextraction of benzodiazepines

Rezaei, Farzad; Yamini, Yadollah; Moradi, Morteza; Daraei, Bahram

doi:10.1016/j.aca.2013.10.026

Cited by 101 publications

(43 citation statements)

References 36 publications

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“…LPME and SPME based on a hollow fiber (HF) have been widely used in the extraction, concentration, and purification of active compounds in TCMs because of the low organic solvent consumption, simplicity, speed, high enrichment factor, and cost‐effectiveness of these techniques. Recently, our research group proposed hollow fiber cell fishing (HFCF) with HPLC on the basis of the previous research and introduced the approach to screen, fish, and identify anticancer active compound groups from TCMs .…”

Section: Introductionmentioning

confidence: 99%

Screening and quantification of anticancer compounds in traditional Chinese medicine by hollow fiber cell fishing and hollow fiber liquid/solid‐phase microextraction

Wang

Chen

et al. 2016

J of Separation Science

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Hollow fiber cell fishing, based on HepG-2, SKOV-3, and ACHN cancer cells, and hollow fiber liquid/solid microextraction with HPLC were developed and introduced for researching the anticancer activity of Rhizoma Curcumae Longae, Radix Curcumae, and Rhizoma Curcumae. The structures of curcumin, demethoxycurcumin, and bisdemethoxycurcumin screened were identified and their contents were determined. The compound target fishing factors and cell apoptosis rates under the effect of the three medicines were determined. The binding sites (cell membrane and cell organelle) and binding target (phospholipase C) on the cell were researched. Hollow fiber liquid/solid-phase microextraction mechanism was analyzed and expounded. Before the application, cell seeding time, growth state and survival rate, compound nonspecific binding, positive and negative controls, repeatability in hollow fiber cell fishing with high-performance liquid chromatography; extraction solvent, sample pH, salt concentration, agitation speed, extraction time, temperature and sample volume in hollow fiber liquid/solid-phase microextraction with high-performance liquid chromatography were investigated. The results demonstrated that the proposed strategy is a simple and quick method to identify bioactive compounds at the cellular level as well as determine their contents (particularly trace levels of the bioactive compounds), analyze multicompound and multitarget entirety effects, and elucidate the efficacious material base in traditional medicine.

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Section: Introductionmentioning

confidence: 99%

Screening and quantification of anticancer compounds in traditional Chinese medicine by hollow fiber cell fishing and hollow fiber liquid/solid‐phase microextraction

Wang

Chen

et al. 2016

J of Separation Science

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“…SFE has been combined with different preconcentration techniques such as dispersive liquid-liquid extraction (DLLME) and vesicular based-supramolecular solvent [22][23][24]. Supramolecular solvents (SUPRASs) constitute environment friendly alternatives to molecular organic ones for analytical extractions [25,26]. In 2007, Ruiz et al [27] developed a supramolecular solvent (SUPRAS) microextraction technique based on analyte partitioning between an alkyl carboxylic acid-based nanostructured solvent and a bulk aqueous sample.…”

Section: Introductionmentioning

confidence: 99%

Supercritical fluid extraction followed by nanostructured supramolecular solvent extraction for extraction of levonorgestrel and megestrol from whole blood samples

Rezaei

Yamini

Asiabi

et al. 2016

The Journal of Supercritical Fluids

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“…LPME , such as single drop microextraction , dispersive liquid–liquid microextraction and hollow fiber LPME , has been increasingly applied to extract analytes from different matrices . Its advantages over conventional extraction procedures are simplicity, rapidity, low organic solvent consumption and high enrichment factor.…”

Section: Introductionmentioning

confidence: 99%

Development of a novel stirrerliquid/solid microextraction method for the separation and enrichment of trace levels of active compounds in traditional Chinese medicine

Wang

Chen

et al. 2016

J of Separation Science

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A novel stirrer-liquid/solid microextraction method was developed for the separation and enrichment of trace levels of curcumin, bisdemethoxycurcumin, and demethoxycurcumin in Rhizoma Curcumae Longae, Radix Curcumae, and Rhizoma Curcumae before their analysis by high-performance liquid chromatography with ultraviolet detection. In the proposed approach, a magnetic stirrer was immersed in decanol to coat its surface completely with decanol, which was used as an extraction platform. The stirrer coated with decanol is not only a power to agitate the sample solution to constantly update the sample on the stirrer surface but also it can adsorb and extract the target analytes. Some effective parameters, including suitable superficial area of stirrer, extraction solvent, sample phase pH, NaCl concentration, stirring rate, extraction time, sample phase volume, were analyzed and selected. Under the optimal conditions, the linearities are 0.0044-2.20 μg/mL, detection limits are 0.3-0.6 ng/mL, and the extraction content per unit length and enrichment factors of the target analytes are 6.24-9.71/mm and 589-917, respectively. Also, the stirrer-liquid/solid microextraction mechanism for the extraction and enrichment of the target analytes was analyzed and expounded. The results showed that stirrer-liquid/solid microextraction is a simple, rapid sample pretreatment approach with a high enrichment factor.

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Supramolecular solvent-based hollow fiber liquid phase microextraction of benzodiazepines

Cited by 101 publications

References 36 publications

Screening and quantification of anticancer compounds in traditional Chinese medicine by hollow fiber cell fishing and hollow fiber liquid/solid‐phase microextraction

Screening and quantification of anticancer compounds in traditional Chinese medicine by hollow fiber cell fishing and hollow fiber liquid/solid‐phase microextraction

Supercritical fluid extraction followed by nanostructured supramolecular solvent extraction for extraction of levonorgestrel and megestrol from whole blood samples

Development of a novel stirrerliquid/solid microextraction method for the separation and enrichment of trace levels of active compounds in traditional Chinese medicine

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