Supratentorial extraventricular anaplastic ependymoma in a child

Abstract

A young child presented to the emergency department of a tertiary care hospital with on and off headache, focal seizures involving the left side of the body, weakness of left upper and lower limbs and vomiting for 2 weeks. Examination showed an alert child with grade 4/5 powers in left upper and lower limbs. Blood investigations were normal. An urgent CT of the brain showed intra-axial mass in the right frontal cerebral cortex, superolateral to the right lateral ventricle. MRI of the brain showed supratentorial extraventricular mass of 5.20 × 3.70 × 3.80 cm, in the right frontal cortex, emitting heterogeneous signals on T1, T2 and fluid-attenuated inversion recovery sequences and impression of astrocytoma, ependymoma or choroid plexus papilloma was made. Complete surgical resection of mass was performed. Histopathology of the mass proved it as WHO grade III anaplastic ependymoma. The child made an uneventful postoperative recovery and radiotherapy was followed.

Adult supratentorial extraventricular anaplastic ependymoma with cerebrospinal fluid dissemination metastases: a case report

“…However, opinions on adjuvant therapy are divergent. For SEAE patients with high Ki-67 positive rate, some studies suggest that if the benefits of postoperative radiotherapy exceed the risk of recurrence of natural therapy in non-children and patients without obvious contraindications, appropriate radiotherapy can be given according to clinical practice ( 12 ). Therefore, the patient in this study was treated with appropriate extended resection of the lesion combined with local radiotherapy and chemotherapy.…”

Cortical Ependymoma Presenting as Subclinical Seizures in a Very Young Child

“…Cortical ependymomas are a relatively uncommon subtype of ependymoma which is extra ventricular. These are uncommon in the pediatric population and have variable clinical courses depending on anatomical location and pathological grading [ 4 ]. They can appear at any age and do not have gender predilection.…”

“…Out of the total, 47 cases were of pediatric age groups, and only nine cases involved very young children less than three years[7]. Two other cases of supratentorial cortical ependymoma in very young children were reported by Mehdi et al andKhilji et al in 2016 and, respectively[2,4]. The reports published in accessible journals were included in a comparison of clinical and radiological features.…”

Supratentorial Extraventricular Anaplastic Ependymoma Presented With Headache in Pregnancy: Case Report and Review of the Literature

“…There are only 47 cases of SEAE in the literature [12,13]. We found 20 reported cases or case series that had the same characteristics as this study prior to June 2014 (Table 1) [6,8,9,12,[14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29]. Only one reported case dealt with pregnancy [4,12,13].…”

“…Supratentorial ependymomas generally originate from the third or, less likely, lateral ventricle walls and grow from there [18,19,32,33]. During their growth, they might reach the cerebral cortex surface and even hold onto the pial surface [8,14].…”