Supratentorial Tumours in Infants and Children

Tiyaworabun, S.; Kazkaz, S.; Nicola, N.; Schirmer, M.

doi:10.1007/978-3-642-95413-9_63

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1987

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“…In a series reported at the Hospital for Sick Children in Toronto be tween 1950 and 1975, the most common age group af fected was between 1 and 6 years [3]. At the University of Düsseldorf 174 supratentorial tumors were seen in children, with a mean age of 9 years, 10 months [4]. Pa tients under 1 year of age accounted for 6% of the Toronto series, and 9.8% in the Düsseldorf series.…”

Section: Introductionmentioning

confidence: 99%

Malignant Supratentorial Gliomas in Childhood

Prados

Levin²

1987

Pediatr Neurosurg

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In this review, we try to review concisely the incidence, genetic predilections, classification, and diagnosis of supratentorial gliomas (astrocytomas, oligodendrogliomas, and mixed gliomas) in children. While surgery and irradiation present the most commonly used and valuable modes of treatment, chemotherapy is a valuable adjunctive therapy. Used either with surgery and radiation in primary untreated patients or at recurrence (progression), chemotherapy can increase useful life. The late effects of treatment are primarily endocrine deficiencies and intellectual impairment; nevertheless, they are not of a degree to preclude aggressive therapy. In order to improve therapy, and because of the small number of patients with supratentorial tumors, collaborative multi-institutional trials should be encouraged.

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Section: Introductionmentioning

confidence: 99%