Süreksiz Referans Sinyalleri ile İnsan Sinovyal Sıvısında Birden Fazla Biyohibrit Mikrorobotun Hareket Kontrolü için Benzetim Çalışmaları

Abstract

It is envisioned that biomedical swarms are going to be used for therapeutic operations in the future. The utilization of a single robot in live tissue is not practical because of the limited volume. In contrast, a large group of microrobots can deliver a useful amount of potent chemicals to the targeted tissue. In this simulation study, a trio of magnetotactic bacteria as a taskforce, Magnetospirillum Gryphiswaldense MSR-1, is maneuvered via adaptive micro-motion control through an external magnetic field. The magnetic field is induced by a single permanent magnet positioned by an open kinematic chain. The coupled dynamics of this small group in the human synovial tissue is simulated with actual magnetic and fluidic properties of the synovial liquid. The common center of mass is tracked by the equation of motion. The overall hydrodynamic interaction amongst all three bacteria is modeled within a synovial medium confined with flat surfaces. A bilateral control scheme is implemented on top of this coupled model. The position of the common center of mass is used as the reference point to the end-effector of the robotic arm. The orientation of the magnetic field is rotated to change the heading of the bacterial-group in an addressable manner. It has been numerically observed that controlling the common swimming direction of multiple bacteria is fairly possible. Results are presented via the rigid-body motion of the robotic task-force as well as the fluidic and magnetic force-components acting on the bacteria along with the bilateral control effort in all axes.