Surface active adrenoceptor compounds prevent the settlement of cyprid larvae of<i>Balanus improvisus</i>

Dahlström, Mia; Mårtensson, Lars-Göran; Jonsson, Per R.; Arnebrant, Thomas; Elwing, Hans

doi:10.1080/08927010009378444

Cited by 99 publications

(63 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2 show significant differences between the settlement recorded using cyprids 0-, 1-, 2-and 5-days-old compared to 3-and 4-days-old. Dahlström et al (2000) observed that storage of cyprids of B. improvisus for more than 24 h decreased settlement by more than 50%. Although this dramatic effect was not observed, younger cyprids (0-day-old) were nevertheless preferred for use in assays, which enabled comparison with previous studies.…”

Section: Discussionmentioning

confidence: 94%

“…Although the settlement behaviour of B. improvisus has been studied with regard to varying environmental conditions (Berntsson & Jonsson 2003;Jonsson et al 2004) and different surface properties (Dahlström et al 2000;Pinori et al 2013), our understanding of the settlement behaviour and surface preferences of B. improvisus lags far behind B. amphitrite. Perhaps the most thoroughly studied aspect of B. improvisus settlement behaviour is the response of cyprids to surface topography (Andersson et al 1999, Berntsson et al 2000a2000b;Berntsson et al 2004).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Correlation between surface chemistry and settlement behaviour in barnacle cyprids (Balanus improvisus)

Fino¹,

Petrone²,

Aldred³

et al. 2013

Biofouling

View full text Add to dashboard Cite

In conclusion, it is demonstrated that despite previous suggestions to the contrary, these two species of barnacle show similar preferences in response to surface free energy; they also respond similarly to charge. These findings have positive implications for the development of novel antifouling coatings and support the importance of consistency in substrate choice for assays designed to compare surface preferences of fouling organisms.

show abstract

Section: Discussionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Correlation between surface chemistry and settlement behaviour in barnacle cyprids (Balanus improvisus)

Fino¹,

Petrone²,

Aldred³

et al. 2013

Biofouling

View full text Add to dashboard Cite

show abstract

“…New environmental regulations generate further restrictions on the use of biocides in industrial formulations [11] for the protection of rivers, lakes, estuaries, coastal waters and groundwater from further deterioration and for protection of biodiversity. There is clearly a need to develop new non-toxic or environmentally benign antifouling alternatives that would be efficient against the most severe fouling organisms such as barnacles, blue mussels, bryozoans and algae [12]. On one hand, there are solutions based on interference with biological adhesion to surfaces; the socalled foul-release coatings.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Activity of the Sponge Metabolites Avarol and Avarone and their Synthetic Derivatives Against Fouling Micro- and Macroorganisms

et al. 2007

View full text Add to dashboard Cite

Abstract:The sesquiterpene hydroquinone avarol (1) was isolated from the marine sponge Dysidea avara, whereas the corresponding quinone, avarone (2), was obtained by oxidation of avarol, and the significantly more lipophilic compounds [3'-(p-chlorophenyl)avarone (3), 3',4'-ethylenedithioavarone (4), 4'-isopropylthioavarone (5), 4'-tertbutylthioavarone (6), 4'-propylthioavarone (7), 4'-octylthioavarone (8)] were obtained by nucleophilic addition of thiols or p-chloroaniline to avarone. All these compounds wereMolecules 2007, 12 1023 tested, at concentrations ranging from 0.5 to 50 µg/mL, for their effect on the settlement of the cyprid stage of Balanus amphitrite, for toxicity to both nauplii and cyprids and for their growth inhibitory activity on marine bacteria (Cobetia marina, Marinobacterium stanieri, Vibrio fischeri and Pseudoalteromonas haloplanktis) and marine fungi (Halosphaeriopsis mediosetigera, Asteromyces cruciatus, Lulworthia uniseptata and Monodictys pelagica).

show abstract

“…The ␣ 2 -adrenoceptor agonist medetomidine was recently discovered to be capable of efficiently inhibiting the settling process of the barnacles B. improvisus and B. amphitrite at nonlethal nanomolar concentrations (Dahlström et al, 2000;Dahlström and Elwing, 2006). Panels coated with medetomidine formulated in an acrylate polymer reduced the recruitment of B. improvisus to the surface by 96% after 4 weeks of exposure in Swedish waters (Dahlströ m et al, 2000).…”

mentioning

confidence: 99%

Octopamine Receptors from the Barnacle Balanus improvisus Are Activated by the α₂-Adrenoceptor Agonist Medetomidine

Lind

Rosenblad²,

Frank

et al. 2010

Mol Pharmacol

View full text Add to dashboard Cite

G protein-coupled octopamine receptors of insects and other invertebrates represent counterparts of adrenoceptors in vertebrate animals. The ␣ 2 -adrenoceptor agonist medetomidine, which is in clinical use as a veterinary sedative agent, was discovered to inhibit the settling process of barnacles, an important step in the ontogeny of this crustacean species. Settling of barnacles onto ship hulls leads to biofouling that has many harmful practical consequences, and medetomidine is currently under development as a novel type of antifouling agent. We now report that medetomidine induces hyperactivity in the barnacle larvae to disrupt the settling process. To identify the molecular targets of medetomidine, we cloned five octopamine receptors from the barnacle Balanus improvisus. We show by phylogenetic analyses that one receptor (BiOct␣) belongs to the ␣-adrenoceptor-like subfamily, and the other four (BiOct␤-R1, BiOct␤-R2, BiOct␤-R3, and BiOct␤-R4) belong to the ␤-adrenoceptor-like octopamine receptor subfamily. Phylogenetic analyses also indicated that B. improvisus has a different repertoire of ␤-adrenoceptor-like octopamine receptors than insects. When expressed in CHO cells, the cloned receptors were activated by both octopamine and medetomidine, resulting in increased intracellular cAMP or calcium levels. Tyramine activated the receptors but with much lesser potency than octopamine. A hypothesis for receptor discrimination between tyramine and octopamine was generated from a homology three-dimensional model. The characterization of B. improvisus octopamine receptors is important for a better functional understanding of these receptors in crustaceans as well as for practical applications in development of environmentally sustainable antifouling agents.

show abstract

Surface active adrenoceptor compounds prevent the settlement of cyprid larvae ofBalanus improvisus

Cited by 99 publications

References 25 publications

Correlation between surface chemistry and settlement behaviour in barnacle cyprids (Balanus improvisus)

Correlation between surface chemistry and settlement behaviour in barnacle cyprids (Balanus improvisus)

Evaluation of the Activity of the Sponge Metabolites Avarol and Avarone and their Synthetic Derivatives Against Fouling Micro- and Macroorganisms

Octopamine Receptors from the Barnacle Balanus improvisus Are Activated by the α₂-Adrenoceptor Agonist Medetomidine

Contact Info

Product

Resources

About

Surface active adrenoceptor compounds prevent the settlement of cyprid larvae ofBalanus improvisus

Cited by 99 publications

References 25 publications

Correlation between surface chemistry and settlement behaviour in barnacle cyprids (Balanus improvisus)

Correlation between surface chemistry and settlement behaviour in barnacle cyprids (Balanus improvisus)

Evaluation of the Activity of the Sponge Metabolites Avarol and Avarone and their Synthetic Derivatives Against Fouling Micro- and Macroorganisms

Octopamine Receptors from the Barnacle Balanus improvisus Are Activated by the α2-Adrenoceptor Agonist Medetomidine

Contact Info

Product

Resources

About

Octopamine Receptors from the Barnacle Balanus improvisus Are Activated by the α₂-Adrenoceptor Agonist Medetomidine