Surface analysis of gutta percha after disinfecting with sodium hypochlorite and silver nanoparticles by atomic force microscopy: An in vitro study

Mishra, Priyesh; Tyagi, Sanjeev

doi:10.4103/1735-3327.237248

Cited by 12 publications

(2 citation statements)

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“…Researchers have also developed gutta-percha coated with AgNPs, creating an antimicrobial shutter for root canal obturation. This innovative approach not only seals the canal effectively but also prevents bacterial regrowth, improving the long-term success of the treatment [103,104]. Furthermore, AgNPs are being integrated as antibacterial additives into materials such as mineral trioxide aggregate (MTA).…”

Section: Silver Nanoparticlesmentioning

confidence: 99%

“…Furthermore, AgNPs are being integrated as antibacterial additives into materials such as mineral trioxide aggregate (MTA). This enhancement has expanded the scope of MTA application, enabling its use in various procedures such as pulp-capping, apexification, and sealing perforations in teeth [103,104]. AgNPs have also been encapsulated in silica, and this combination was very strategic because it showed major and longer antimicrobial activity, resulting in minimal biofilm regrowth after 7 days of treatment instead of AgNPs alone, where regrowth occurred after 2 days [105].…”

Section: Silver Nanoparticlesmentioning

confidence: 99%

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Nanoparticles and Their Antibacterial Application in Endodontics

Capuano,

Amato,

Dell’Annunziata

et al. 2023

Antibiotics

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Root canal treatment represents a significant challenge as current cleaning and disinfection methodologies fail to remove persistent bacterial biofilms within the intricate anatomical structures. Recently, the field of nanotechnology has emerged as a promising frontier with numerous biomedical applications. Among the most notable contributions of nanotechnology are nanoparticles, which possess antimicrobial, antifungal, and antiviral properties. Nanoparticles cause the destructuring of bacterial walls, increasing the permeability of the cell membrane, stimulating the generation of reactive oxygen species, and interrupting the replication of deoxyribonucleic acid through the controlled release of ions. Thus, they could revolutionize endodontics, obtaining superior results and guaranteeing a promising short- and long-term prognosis. Therefore, chitosan, silver, graphene, poly(lactic) co-glycolic acid, bioactive glass, mesoporous calcium silicate, hydroxyapatite, zirconia, glucose oxidase magnetic, copper, and zinc oxide nanoparticles in endodontic therapy have been investigated in the present review. The diversified antimicrobial mechanisms of action, the numerous applications, and the high degree of clinical safety could encourage the scientific community to adopt nanoparticles as potential drugs for the treatment of endodontic diseases, overcoming the limitations related to antibiotic resistance and eradication of the biofilm.

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Section: Silver Nanoparticlesmentioning

confidence: 99%

Section: Silver Nanoparticlesmentioning

confidence: 99%