2020
DOI: 10.1039/d0ra03133j
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Surface coating determines the inflammatory potential of magnetite nanoparticles in murine renal podocytes and mesangial cells

Abstract: Primary renal podocytes are more susceptible to MNPs exposure than primary renal mesangial cells.

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Cited by 3 publications
(1 citation statement)
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“…Interestingly, the magnetic nanospheres (PEG-SO-MNPs coated with polylactic- co -glycolic acid, PLGA) were taken up by A549 cells to the same extent as BSA-SO-MNPs, even though their hydrodynamic particle size was more than five times larger [ 44 ]. A less efficient uptake of BSA-coated MNPs compared to PEG-coated MNPs has been observed also in primary murine podocytes [ 45 ]. Superparamagnetic iron oxide nanoparticles covered with BSA were shown to possess a lower affinity to the cellular membrane [ 42 ].…”
Section: Discussionmentioning
confidence: 99%
“…Interestingly, the magnetic nanospheres (PEG-SO-MNPs coated with polylactic- co -glycolic acid, PLGA) were taken up by A549 cells to the same extent as BSA-SO-MNPs, even though their hydrodynamic particle size was more than five times larger [ 44 ]. A less efficient uptake of BSA-coated MNPs compared to PEG-coated MNPs has been observed also in primary murine podocytes [ 45 ]. Superparamagnetic iron oxide nanoparticles covered with BSA were shown to possess a lower affinity to the cellular membrane [ 42 ].…”
Section: Discussionmentioning
confidence: 99%