Surface-enhanced Raman Scattering of Self-assembled Superstructures

Feng, Enduo; Tian, Yang

doi:10.1007/s40242-021-1263-7

Cited by 6 publications

(5 citation statements)

References 216 publications

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“…28 Upon chain assembly, the MBA ligands on the surface of AuNPs are expected to become trapped at the nanoparticle junctions, creating SERS hotspots. [29][30][31] In the ensemble measurements of the colloidal aggregates, Sample 1d shows 65 times stronger SERS intensity than the MBA-stabilized single AuNPs, with an effective enhancement factor (EF) of 1.01 Â 10 5 (see the ESI † for details). The SERS intensity first increases linearly in 60 min, gradually reaches a plateau in 2 h, and then decreases slightly in 4 h (Fig.…”

Section: Resultsmentioning

confidence: 99%

A general method for precise chain assembly of noble metal nanoparticles

Peng

Zhang

Xue

et al. 2023

Mater. Chem. Front.

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Section: Resultsmentioning

confidence: 99%

A general method for precise chain assembly of noble metal nanoparticles

Peng

Zhang

Xue

et al. 2023

Mater. Chem. Front.

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“…2 B presents the typical procedure of SERS metabolite detection: firstly, the metabolite samples are collected and added onto the SERS-active nanostructures for molecular adsorption; then, the exposure of samples to laser excitations induces high SERS signal, which can be detected by the Raman spectrometer; finally, the obtained SERS signals are processed and analyzed for quantification. The design of SERS substrates follows the guidelines of generating more plasmonic hotspots [ [85] , [86] , [87] , [88] ]. As shown in Fig.…”

Section: Main Metabolic Molecules Detecting Methodsmentioning

confidence: 99%

Human metabolite detection by surface-enhanced Raman spectroscopy

Liu

2022

Materials Today Bio

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Metabolites are important biomarkers in human body fluids, conveying direct information of cellular activities and physical conditions. Metabolite detection has long been a research hotspot in the field of biology and medicine. Surface-enhanced Raman spectroscopy (SERS), based on the molecular “fingerprint” of Raman spectrum and the enormous signal enhancement (down to a single-molecule level) by plasmonic nanomaterials, has proven to be a novel and powerful tool for metabolite detection. SERS provides favorable properties such as ultra-sensitive, label-free, rapid, specific, and non-destructive detection processes. In this review, we summarized the progress in recent 10 years on SERS-based sensing of endogenous metabolites at the cellular level, in tissues, and in biofluids, as well as drug metabolites in biofluids. We made detailed discussions on the challenges and optimization methods of SERS technique in metabolite detection. The combination of SERS with modern biomedical technology were also anticipated.

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“…Raman scattering refers to an inelastic light scattering process that provides a vibrational spectrum representing chemical structure information [85][86][87][88]. However, the Raman scattering is a weak process, and generally the light intensity is only approximately 10 −10 of the incident light intensity [89][90][91]. Surface-enhanced Raman scattering (SERS) is based on the enhancement effects of the rough surface of noble metals, which are 10 4 -10 7 times stronger than traditional Raman scattering signals [92][93][94][95].…”

Section: Microrobots In Surface-enhanced Raman Scattering Biosensingmentioning

confidence: 99%

Emerging Roles of Microrobots for Enhancing the Sensitivity of Biosensors

Lu,

Bao,

Wei

et al. 2023

Nanomaterials

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To meet the increasing needs of point-of-care testing in clinical diagnosis and daily health monitoring, numerous cutting-edge techniques have emerged to upgrade current portable biosensors with higher sensitivity, smaller size, and better intelligence. In particular, due to the controlled locomotion characteristics in the micro/nano scale, microrobots can effectively enhance the sensitivity of biosensors by disrupting conventional passive diffusion into an active enrichment during the test. In addition, microrobots are ideal to create biosensors with functions of on-demand delivery, transportation, and multi-objective detections with the capability of actively controlled motion. In this review, five types of portable biosensors and their integration with microrobots are critically introduced. Microrobots can enhance the detection signal in fluorescence intensity and surface-enhanced Raman scattering detection via the active enrichment. The existence and quantity of detection substances also affect the motion state of microrobots for the locomotion-based detection. In addition, microrobots realize the indirect detection of the bio-molecules by functionalizing their surfaces in the electrochemical current and electrochemical impedance spectroscopy detections. We pay a special focus on the roles of microrobots with active locomotion to enhance the detection performance of portable sensors. At last, perspectives and future trends of microrobots in biosensing are also discussed.

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Surface-enhanced Raman Scattering of Self-assembled Superstructures

Cited by 6 publications

References 216 publications

A general method for precise chain assembly of noble metal nanoparticles

A general method for precise chain assembly of noble metal nanoparticles

Human metabolite detection by surface-enhanced Raman spectroscopy

Emerging Roles of Microrobots for Enhancing the Sensitivity of Biosensors

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