Surface-enhanced Raman scattering via entrapment of colloidal plasmonic nanocrystals by laser generated microbubbles on random gold nano-islands

Kang, Zhiwen; Chen, Jiajie; Ho, Ho-Pui

doi:10.1039/c6nr00375c

Cited by 36 publications

(47 citation statements)

References 40 publications

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“…As shown in Table S1 in the Supporting Information, we also evaluated the detection limit for two other fluorescence compounds Rhodamine 6G (R6G) and Nile Red with octanol-water partition coefficients (log P) of −0.77 and 5, respectively. [32,33] Here, the low detection concentration of R6G may mainly be attributed to the concentration effect from evaporation and accumulation on the droplet surface due to similar partitioning of R6G in octanol and in water. [32,33] Here, the low detection concentration of R6G may mainly be attributed to the concentration effect from evaporation and accumulation on the droplet surface due to similar partitioning of R6G in octanol and in water.…”

Section: Fluorescence Detection Of Model Compoundsmentioning

confidence: 95%

“…[29,30] As summarized in Figures S2 and S3 in the Supporting Information, the limit of detection (LOD) of R6G is as low as 10 −9 m, which is comparable to surface-enhanced Raman scattering [31] and better than the LOD obtained using other approaches, such as well-defined Ag nanocrystals in solution or microfluidic nanopillars. [32,33] Here, the low detection concentration of R6G may mainly be attributed to the concentration effect from evaporation and accumulation on the droplet surface due to similar partitioning of R6G in octanol and in water. Remarkably, the LOD of Nile Red was found to be 10 −12 m, possibly due to its higher partition coefficient compared to Nile Blue and R6G.…”

Section: Fluorescence Detection Of Model Compoundsmentioning

confidence: 99%

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One‐Step Nanoextraction and Ultrafast Microanalysis Based on Nanodroplet Formation in an Evaporating Ternary Liquid Microfilm

Qian

Yamada

Wei

et al. 2019

Adv Materials Technologies

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in chemical analysis workflow is sample pretreatment to extract the analytes before detection. The recent development of dispersive liquid-liquid microextraction (DLLME) has stimulated progress for extracting and preconcentrating trace hydrophobic analytes from aqueous solutions both rapidly and efficiently. [4][5][6] DLLME is based on spontaneous emulsification upon mixing of a water-insoluble extractant, a dispersive solvent, and an analyte aqueous solution. [7,8] The hydrophobic analyte could be rapidly extracted into extractant nanodroplets because of the higher solubility of the analyte in the extractant than in water. The large surface area of nanodroplets enhances the transfer of the analyte from the surrounding solution to the droplets. Relying on the combination of DLLME and various detection techniques, such as inductively coupled plasma optical emission spectrometry or fluorescence spectrometry, trace chemical analysis has been achieved for diverse applications. [9][10][11] However, these existing approaches require significant improvement due to their time-consuming nature, their requirement for specialized equipment in droplet separation and for large volumes of the analyte solution. [12,13] Many studies have focused on concentrating compounds from a single sessile drop evaporation. [14][15][16][17] A common issue comes from the coffee stain effect that leads to uncontrolled deposition of the analyte on the substrate rather than into a focused spot. Although an evaporating drop can shrink isotropically on superhydrophobic surfaces, micro/nanoscale structures on these surfaces can influence solute deposition, in particular at the final stage of evaporation when the drop size becomes comparable with the structures. [18] Supersensitive detection can be achieved for the materials deposited on highly ordered nanostructures on the substrate by using the plasmonic effect. [19] However, these nanostructures are difficult to fabricate for fast and high throughput analysis. Recent work on drop evaporation of ternary liquid mixtures shows advantageous features that may lead to unpinned drop for solute concentrating. [20,21] Selective evaporation of the volatile co-solvent (ethanol) in the mixture leads to oversaturation of oil and consequently spontaneously formation of tiny droplets. This phenomenon of Preconcentration is key for detection from an extremely low concentration solution, but requires separation steps from a large volume of samples using extracting solvents. Here, a simple approach is presented for ultrafast and sensitive microanalysis from a tiny volume of aqueous solutions. In this approach, liquid-liquid nanoextraction in an evaporating thin liquid film on a spinning substrate is coupled with quantitative analysis in one step. The approach is exemplified using a liquid mixture comprising a target compound to be analyzed in water, mixed with extractant oil and co-solvent ethanol. With rapid evaporation of ethanol, nanodroplets of oil form spontaneously in the film. The compounds are highly conce...

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Section: Fluorescence Detection Of Model Compoundsmentioning

confidence: 95%

Section: Fluorescence Detection Of Model Compoundsmentioning

confidence: 99%

One‐Step Nanoextraction and Ultrafast Microanalysis Based on Nanodroplet Formation in an Evaporating Ternary Liquid Microfilm

Qian

Yamada

Wei

et al. 2019

Adv Materials Technologies

View full text Add to dashboard Cite

show abstract

“…In addition, the powerful hydrodynamic phenomenon of microbubbles can be produced to enhance optofluidic systems due to their high optothermal conversion efficiency. [20,[55][56][57] Microbubbles have found a range of applica tions in microfluidic systems, including the prominent ability to induce strong Marangoni convection by creating an uneven thermal distribution at the liquid-air interface to support long range actuation and particle transportation. [18,56,58] Because it can be used to manipulate microfluids in a noncontact manner, optofluidic actuation has a unique ability to enhance the sensing performance of microfluidic systems and simplify their design.…”

Section: Optofluidic Actuationmentioning

confidence: 99%

“…Chen et al then improved this technique by using photothermal conversion and surface tension to control gold nanostructures beneath the fluidic channel instead of suspended photothermal particles, providing a possible solution to all three challenges in one microfluidic system. In addition, the powerful hydrodynamic phenomenon of microbubbles can be produced to enhance optofluidic systems due to their high optothermal conversion efficiency . Microbubbles have found a range of applications in microfluidic systems, including the prominent ability to induce strong Marangoni convection by creating an uneven thermal distribution at the liquid–air interface to support long‐range actuation and particle transportation .…”

Section: Introductionmentioning

confidence: 99%

Thermal Optofluidics: Principles and Applications

Chen

Loo

Wang

et al. 2019

Advanced Optical Materials

Self Cite

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Thermal optofluidics is an emerging field that promises to create numerous research and application opportunities in biophysics, biochemistry, and clinical biology. Innovation in plasmonic optics has led to the development of various invaluable tools in the fields of biosensing and microfluidic manipulation. The optothermal effect originates from light–matter interactions during photon–phonon conversion, which can lead to micro‐ or nanoscale inhomogeneities in the thermal distribution. This further induces a series of hydrodynamic phenomena such as natural convection, Marangoni convection, thermophoresis, the electrolyte Seebeck effect, depletion forces, and interfacial effects in colloidal particles. Light–matter interactions are particularly important for three aspects of microfluidics, namely the motion of colloidal particles, fluidic actuation, and biochemical reactions. This review first systematically elucidates the role of both nanoscale plasmonic thermal generation and heat‐induced fluidic motion in optofluidic microsystems. Then, recent state‐of‐the‐art thermal optofluidic applications of the above‐listed three aspects are presented. The paper aims to provide an insightful reference for future research in optofluidic biochemical systems.

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“…Degassed water is still capable of photothermal microbubble generation, however the overall saturated bubble is reduced in size [10]. Using a plasmonic substrate as the light absorber to generate microbubbles has considerably reduced the necessary laser power to generate a plasmonic microbubble and successfully assembled micro-and nanoparticles for on-chip sensing devices [11].…”

Section: Introductionmentioning

confidence: 99%

Directed assembly and concentrating of micro/nanoparticles, cells, and vesicles via low-power near-infrared laser generated plasmonic microbubbles

Ohannesian¹,

Li²,

Misbah³

et al. 2020

Preprint

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Directed assembly and concentrating of micro-and nanoparticles via laser generated plasmonic microbubbles in a liquid environment is an emerging technology. For effective heating, visible light has been primarily employed in existing demonstrations. In this paper, we demonstrate a new plasmonic platform based on nanoporous gold disk (NPGD) array. Thanks to the highly tunable localized surface plasmon resonance of the NPGD array, microbubble of controlled size can be generated by near-infrared (NIR) light. Using NIR light provides several key advantages over visible light in less interference with standard microscopy and fluorescence imaging, preventing fluorescence photobleaching, less susceptible to absorption and scattering in turbid biological media, and much reduced photochemistry, phototoxicity and whatsoever. The large surface-to-volume ratio of NPGD further facilitates the heat transfer from these gold nanoheaters to the surroundings, achieving unprecedented low-power operation. While the microbubble is formed, the surrounding liquid circulates and direct microparticles randomly dispersed in the liquid to the bottom NPGD surface, yielding unique assemblies of microstructures. Such capability can also be employed in concentrating suspended colloidal nanoparticles at desirable sites and with preferred configuration, both enhancing the sensor performance. In addition to various micro-and nanoparticles, the plasmonic microbubbles are also shown to collect biological cells and nanovesicles. By using a spatial light modulator (SLM) to project the laser in arbitrary patterns, parallel assembly can be achieved to fabricate an array of clusters. These assemblies have been characterized using optical microscopy, scanning electron microscope, hyperspectral localized surface plasmon resonance imaging and hyperspectral Raman imaging.

show abstract

Surface-enhanced Raman scattering via entrapment of colloidal plasmonic nanocrystals by laser generated microbubbles on random gold nano-islands

Cited by 36 publications

References 40 publications

One‐Step Nanoextraction and Ultrafast Microanalysis Based on Nanodroplet Formation in an Evaporating Ternary Liquid Microfilm

One‐Step Nanoextraction and Ultrafast Microanalysis Based on Nanodroplet Formation in an Evaporating Ternary Liquid Microfilm

Thermal Optofluidics: Principles and Applications

Directed assembly and concentrating of micro/nanoparticles, cells, and vesicles via low-power near-infrared laser generated plasmonic microbubbles

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