Surface-enhanced Raman spectroscopy of centrifuged blood serum samples of diabetic type II patients by using 50KDa filter devices

Surface-enhanced Raman spectroscopy for characterization of filtrates of blood serum samples from patients with tuberculosis obtained by 50 kDa filtration devices

“…Raman spectroscopy of bodily uids, notably blood serum, can be used to identify the chemical ngerprints of samples. 12,13 Raman spectroscopy is an efficient qualitative and quantitative analytical tool for rapidly obtaining critical information. 14 Although weak signal intensity oen occurs with Raman spectroscopy, it is rapid, inexpensive, and precise.…”

Tunable Surface Plasmon-Polaritons Interaction in All-Metal Pyramidal Metasurfaces: Unveiling Principles and Significance for Biosensing Applications

“…14,15 Addressing these challenges requires innovative methodologies to engineer highly efficient plasmonic devices capable of maximizing electromagnetic field concentration at the analyte region. 10,16,17 Furthermore, these nanostructures must seamlessly integrate with microfluidic technology to ensure easy implementation in future PoC applications. On the other hand, the flourishing field of optical metasurfaces is attracting growing interest due to its remarkable ability to precisely manipulate and adapt optical properties.…”

“…However, despite significant progress, persistent challenges hinder the transition of plasmonic biosensors from research laboratories to hand-held devices. In SERS, for example, a notable challenge arises from the limited signal amplification primarily due to the inhibited interaction between analyte molecules and the typically small electromagnetic field on the surface of dielectric substrates. − Moreover, traditional plasmonic biosensing methods encounter limitations due to relatively modest electromagnetic field enhancements in flat planar surfaces or grating structures. , Addressing these challenges requires innovative methodologies to engineer highly efficient plasmonic devices capable of maximizing electromagnetic field concentration at the analyte region. ,, Furthermore, these nanostructures must seamlessly integrate with microfluidic technology to ensure easy implementation in future PoC applications. On the other hand, the flourishing field of optical metasurfaces is attracting growing interest due to its remarkable ability to precisely manipulate and adapt optical properties. − These metasurfaces harness the near-field overlap between neighboring nanoparticles, mimicking the electronic bands found in well-localized atomic orbitals.…”