“…Half of the identified articles were published until 1994, and three-quarters of these were published until 2003. Studies were performed in 20 different countries 12,17,20,41,43,49-111 (cited in Table, Supplemental Digital Content 2 , http://links.lww.com/PRS/D415). The most commonly used animal species was the rabbit (57.1 percent), followed by the rat (26.4 percent), the dog (14.3 percent), and the pig (2.2 percent).…”