Surface-mediated effects on porous polymer monolith formation within capillaries

Surface-area expansion with monolithic open tubular columns

“…Such modifications strongly impact on the surface properties. Gibson et al [37] have studied the effects of surface modification of the wall of the fused-silica capillary on the thickness and the morphology of the sheath surrounding the porous polymer monolith. They found a correlation between surface hydrophobicity (assessed from contact-angle measurements) and the extent of connection established by porous polymers, based on butyl acrylate and 1,3-butanediol diacrylate, with greater hydrophobicity leading to lower levels of connections being made with the sheath.…”

An Insight to Chiral Monolith for Enantioselective Nano and Micro HPLC: Preparation and Applications

“…26 Typically, for monolithic media, poor solvents of the chosen monomers are utilised for formation of the macro-throughpores sought for liquid flow. 28 Chiral moieties may be inserted into the slurry mixture pre-polymerization in order to inherently functionalize the monolith with enantioselective ability. Therefore, in preparation techniques of most organic polymeric monolithic stationary phases, phase separation between growing polymer chains and porogenic solvent occurs rapidly and the coarsening of the monolithic structure inherently leads to heterogeneous macroporous structures composed of micrometer-size globular particles.…”

“…Therefore, in preparation techniques of most organic polymeric monolithic stationary phases, phase separation between growing polymer chains and porogenic solvent occurs rapidly and the coarsening of the monolithic structure inherently leads to heterogeneous macroporous structures composed of micrometer-size globular particles. 28 The effects of down-scaling on porosity and packing densities are also a consideration 31 in the synthesis of polymer-based monoliths for use in nano-HPLC. 27 A common monomeric source for radical initiated addition polymerization is butyl acrylate with 1,3-butanediol diacrylate as crosslinker and 2,2 0 -azobis(2-methylpropionitrile (AIBN) as initiator.…”

Porous Polymer Monolith Microextraction Platform for Online GC-MS Applications

“…Thus, polymer microstructure can be controlled by rate of reaction, monomer/porogen ratio, type of porogenic solvents and fraction of cross-linking monomers. Detailed descriptions of various chemistries, and characterization of resulting monoliths can be found in references (Gibson et al 2008& Svec, 2010.…”