Surface Modification of 316L SS Implants by Applying Bioglass/Gelatin/Polycaprolactone Composite Coatings for Biomedical Applications

Abstract

In this study, various composites of bioglass/gelatin/polycaprolactone (BG/GE/PCL) were produced and coated on the surface of 316L stainless steel (SS) to improve its bioactivity. X-ray diffractometry (XRD), scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS) were utilized to characterize the specimens. The results showed that bioglass particles were distributed uniformly in the coating. By increasing the wt.% of bioglass in the nanocomposite coatings, the surface roughness and adhesion strength increased. The corrosion behavior of GE/PCL (PCL-10 wt.% gelatin coated on 316L SS) and 3BG/GE/PCL (GE/PCL including 3 wt.% bioglass coated on 316L SS) samples were studied in PBS solution. The results demonstrated that 3BG/GE/PCL sample improved the corrosion resistance drastically compared to the GE/PCL specimen. In vitro bioactivity of samples was examined after soaking the specimens for 7, 14 and 28 days in simulated body fluid (SBF). The results showed a significant apatite formation on the surface of 3BG/GE/PCL samples. The cell viability evaluation was performed using 3- (4, 5-dimethylthiazol-2-yl)-2,5 diphenyltetrazoliumbromide (MTT) tests which confirmed the enhanced cell viability on the surface of 3BG/GE/PCL samples. The in vivo behavior of specimens illustrated no toxicity and inflammatory response and was in a good agreement with the results obtained from the in vitro test.

Al2O3-ZnO atomic layer deposited nanolaminates for improving mechanical and corrosion properties of sputtered CrN coatings

“…AISI 316L Stainless Steel is widely used as structural material in marine, biomedical [1] and industrial applications due to its specific strength, fracture toughness and excellent corrosion resistance. However, AISI 316L is subject to localized pitting corrosion in chloride ions rich environment due to the breakdown of the chromium oxide thin passive layer enriched surface [2].…”

Bioactive Glass—An Extensive Study of the Preparation and Coating Methods

“…The EIS analysis has shown that the deposited coating increases the corrosion resistance of the substrate. In vivo animal tests have shown that there is no inflammation and granulation of tissues, formation of fibrotic tissue or the appearance of a toxic effect at the site of implantation [202].…”

Investigation of Roughness, Morphology, and Wettability Characteristics of Biopolymer Composite Coating on SS 316L for Biomedical Applications

“…Since nanosilver and biotin are biocompatible and have protective qualities, they are added to biopolymer composites to coat stainless steel 316L in biomedical applications [ 19 , 20 ]. Nanosilver possesses antimicrobial properties [ 21 ], making it a valuable component that can contribute to lowering the risk of infection [ 19 ].…”