Surface modification of acid-functionalized mesoporous gamma-alumina for non-fission 99Mo/99mTc generator

ESTIMASI DOSIS 99mTc-PERTEHNETAT DARI GENERATOR 99Mo / 99mTc NON-FISI PADA ANAK-ANAK USIA 1-15 TAHUN UNTUK PROSEDUR DIAGNOSTIK

“…99m Tc merupakan radioisotop pemancar gamma yang memiliki energi 140 keV dan waktu paro 6 jam, dimana 99m Tc akan berada di dalam tubuh tidak begitu lama untuk mencapai organ targetnya [6][7][8][9]. 99m Tc merupakan anak radioisotop dari 99 Mo yang dapat diproduksi dengan reaksi fisi dan non fisi [10][11][12]. 99m Tc radioisotop diproduksi menggunakan sistem generator, suatu alat yang terdiri dari kolom alumina, dimana 99 Mo akan diserap ke dalam senyawa kimia berupa [ 99 Mo]MoO4 2sehingga peluruhan 99 Mo akan menjadi [ 99m Tc]TcO4 - [13][14][15].…”

Gamma spectrometer calibration of liquid standard sources of Mix 133Ba, 137Cs and 60Co toward the measurement of 99Mo breakthrough of 99Mo/99mTc generator

“…The energy were calibrated correspond to the channel in multi channel annalyzer (MCA) with a multiple gamma-ray emitting source, which contained of mix 133Ba, 137Cs and 60Co in liquid 10 mL form inside moly assay canister, gave the result as seen in equation ( 1)- (3). The advantage of this standard sources is the range of low-high energy spectrum [14], so that it could quantify the radionuclide sample sources whose energy lies between this range (276 -1332 keV).…”

“…Radioactive nuclides such as 99m Tc is increasingly used in clinical diagnosis application of nuclear medicine [1][2]. In the hospital and research center, the 99m Tc radionuclide is generally provided from the 99 Mo/ 99m Tc generator [3][4] and the 99 Mo breaktrough (impurity) must meet the criteria of 0.15 uCi of 99 Mo/ mCi of 99m Tc from the International Atomic Energy Agency (IAEA) safety standard. This be able to assess the main possible impurities of radionuclide present in the product.…”