Surface modification of additively manufactured metallic biomaterials with active antipathogenic properties

Nouri, Alireza; Shirvan, Anahita Rohani; Li, Yuncang; Wen, Cuié

doi:10.1016/j.smmf.2022.100001

Cited by 23 publications

(14 citation statements)

References 204 publications

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“…[197,198] Al surfaces can be treated with a variety of hard coatings or mechanical finishes (e.g., polishing, sandblasting, anodic or oxide finishes) to increase corrosion resistance. [199][200][201] Brass or copper rivets and repeated plating of copper, nickel, and chromium are among the significant but minor uses of other metals. [107] Carbon fiber and Ti uprights are lighter than Al and as strong as steel; however, orthoses made of these materials are more expensive.…”

Section: Metalsmentioning

confidence: 99%

Materials and Manufacturing for Ankle–Foot Orthoses: A Review

Nouri

Wang

et al. 2023

Adv Eng Mater

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Ankle‐foot orthoses (AFOs) assist patients with gait impairment by correcting ankle and foot deformities, restoring mobility, reducing pain, and providing protection and immobilization. AFOs can beneficially manage various types of gait pathologies, including foot drop, crouch gait, equinus gait, and stiff knee gait. AFOs are produced in prefabricated or custom‐made forms in various designs. The selection criteria for the fabrication of an AFO are the duration of usage, the amount of applied force, the degree of axial loading, the patient’s skin condition, and the cost. The accessibility of diverse materials in the past century has greatly advanced orthoses. The ideal orthotic materials must be light, stiff, and strong, and are made of plastics, metals, polymer‐based composites, leather, or a hybrid of different materials. Deeper understanding of the materials employed in the fabrication of AFOs will lead to more advanced and efficient orthoses, which can improve patients’ ability to ambulate in the real world. The present review provides insight into the various materials utilized for the fabrication of AFOs and describes the benefits and challenges associated with these materials. An attempt has also been made to highlight typical gait pathologies and design concepts in response to these.This article is protected by copyright. All rights reserved.

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Section: Metalsmentioning

confidence: 99%

Materials and Manufacturing for Ankle–Foot Orthoses: A Review

Nouri

Wang

et al. 2023

Adv Eng Mater

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“…Various categories of release-based antibacterial polymer coatings with multifunctionality were created, including multi-release, multiapproach, and multi-property [51]. First of all, multi-release coatings are known for their reduction in bacterial resistance induction as well as the synergistic antibacterial action [52]. Materials, such as antibiotics and metals could be incorporated with silver to resist bacteria, resulting in better synergistic results.…”

Section: Multi-functionalitymentioning

confidence: 99%

A Review on Polymer Based Antimicrobial Coating

Musa

Chang

Teow

et al. 2022

J Biochem Microbiol Biotechnol

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Antimicrobial coatings have become a key component of the worldwide microbial infection mitigation plan. A wide range of alternatives for designing surfaces with antimicrobial qualities is now accessible, attributed to the recent developments in materials science, biotechnology, and environmental microbiology. Antimicrobial coatings have a big role to control the spread of disease, preventing microbial colonisation on the substrate used in various applications. The antimicrobial coatings could be formed on the substrate by utilizing the polymer with antimicrobial properties or incorporating the antimicrobial agents into the polymer. By manipulating the use of polymers and surrounding conditions, the antimicrobial activity of the coating could be tailored accordingly. Due to the difference in physicochemical properties of both antimicrobial polymers and agents, the antimicrobial mechanism could be demonstrated by antimicrobial agent release, antimicrobial agent retention, contact-killing, and anti-adhesion. This paper provides information on antimicrobial coatings, in terms of the synthesis methods, antimicrobial mechanism, influencing factors, and applications in various industries.

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“…One of the current strategies for decreasing the potential fungal adherence is concentrated on the development of coating materials and/or surface modifications of titanium implants, for example, with TiO 2 nanomaterial. The goal of these modifications has been to repel or inhibit C. albicans biofilm formation. − The promising results of such surface modifications have inspired researchers to investigate other potential coatings with enhanced performances.…”

Section: Introductionmentioning

confidence: 99%

Effects of TiS₂ on Inhibiting Candida albicans Biofilm Formation and Its Compatibility with Human Gingival Fibroblasts in Titanium Implants

Fathi-Hafshejani

Tinker

Freel

et al. 2023

ACS Appl. Bio Mater.

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Titanium is widely used in medical devices, such as dental and orthopedic implants, due to its excellent mechanical properties, low toxicity, and biocompatibility. However, the titanium surface has the risk of microbial biofilm formation, which results in infections from species such as Candida albicans (C. albicans). This kind of biofilm prevents antifungal therapy and complicates the treatment of infectious diseases associated with implanted devices. It is critical to developing a feasible surface to decrease microbial growth while not interfering with the growth of the host cells. This study reports the influence of titanium surface modification to titanium disulfide (TiS2) on inhibiting C. albicans biofilm formation while allowing the attachment of human gingival fibroblasts (HGFs) on their surface. The surface of titanium parts is directly converted to structured titanium and TiS2 using direct laser processing and crystal growth methods. C. albicans adhesion and colonization are then investigated on these surfaces by the colony counting assay and reactive oxygen species (ROS) assay, using 2′,7′-dichlorofluorescin diacetate (DCFH-DA) and microscopy images. Also, the viability and adhesion of HGFs on these surfaces are investigated to show their adhesion and biocompatibility. Titanium samples with the TiS2 surface show both C. albicans biofilm inhibition and HGF attachment. This study provides insight into designing and manufacturing titanium biomedical implants.

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Surface modification of additively manufactured metallic biomaterials with active antipathogenic properties

Cited by 23 publications

References 204 publications

Materials and Manufacturing for Ankle–Foot Orthoses: A Review

Materials and Manufacturing for Ankle–Foot Orthoses: A Review

A Review on Polymer Based Antimicrobial Coating

Effects of TiS₂ on Inhibiting Candida albicans Biofilm Formation and Its Compatibility with Human Gingival Fibroblasts in Titanium Implants

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Surface modification of additively manufactured metallic biomaterials with active antipathogenic properties

Cited by 23 publications

References 204 publications

Materials and Manufacturing for Ankle–Foot Orthoses: A Review

Materials and Manufacturing for Ankle–Foot Orthoses: A Review

A Review on Polymer Based Antimicrobial Coating

Effects of TiS2 on Inhibiting Candida albicans Biofilm Formation and Its Compatibility with Human Gingival Fibroblasts in Titanium Implants

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Product

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Effects of TiS₂ on Inhibiting Candida albicans Biofilm Formation and Its Compatibility with Human Gingival Fibroblasts in Titanium Implants