Surface modification of polyacrylonitrile nanofibrous membranes with superior antibacterial and easy-cleaning properties through hydrophilic flexible spacers

Synthesis of Novel Glycidol Copolymers with Pendant Alkene and Hydroxyl Groups

“…Due to the coexistence of double bonds and hydroxyl groups in the side chain, it provides the reactive sites in the copolymer, just like a chemical reaction platform, for further chemical modification and functionalization. [10,[28][29][30] …”

“…[1][2][3][4] It has the following advantages: a good solubility in water and most organic solvents, unique anti-fouling [5][6][7][8][9] and anti-bacteria properties, [10][11][12][13] low toxicity which is approved by US FDA, and so on. The PEG, however, only has one or two active chemical group(s) (hydroxyl group) at the end of its backbone, which limits its combining ability with other functional molecules and subsequently limits its practical applications in a variety of application environments.…”

Surface-modified polyacrylonitrile nanofibres as supports

“…Following PHGH conjugation, the nitrogen concentration increased, while the oxygen concentration decreased. These changes are to be expected on the basis of the composition of the chemical reagents [2].…”

“…Ishimura et al [24] reduced the PAN-nfs with LiAlH 4 and immobilized penicillin acylase on them to study the activity of the enzyme after the attachment on the PAN-nf-NH 2 in terms of specific activity and immobilization yields. Mei et al [2] reported the successful immobilization of polyhexamethyleneguanidine hydrochloride (PHGH) using lyceroldiglycidylether (GDGE) and poly(ethylene glycol)diglycidyl ether (PEGDGE) as (Table 1). After introduction of hydrophilic flexible spacers (GDGE and PEGDGE), the atom percentage of oxygen increased significantly, while the nitrogen concentration decreased.…”

“…Covalent binding of these materials is always emphasized for the sake of reusability and to eliminate concerns regarding adverse effects that may be associated with leaching of any of these materials [1]. Tethering of enzymes or antibacterial agents to solid supports via functional groups can give characteristics, such as specific absorption, greater stability, and enhanced biological activities [1,2]. Surface-modified PAN-nfs have extensively been used as supports for different enzymes for various industrial and biomedical applications, such as biocatalysts, bioreactors, and protein filtration [3,4].…”