Surface modification of polysulfone hollow fiber membrane for extracorporeal membrane oxygenator using low‐temperature plasma treatment

Zheng, Zhi; Wang, Weiping; Huang, Xin; Wu, Fan; Li, Lei

doi:10.1002/ppap.201700122

Cited by 20 publications

(14 citation statements)

References 34 publications

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“…The low-temperature plasma treatment (LTPT) was extensively used in membrane surface modification. Zheng et al [ 77 ] reported a successful surface modification of the PSF membrane via LTPT and grafting acrylic acid (AA) and PEG, 2-methacryloyloxyethyl phosphorylcholine (MPC), heparin and collagen ( Figure 9 ). Zhang et al [ 78 ] described a surface modification of the PSF via ammonia–oxygen (NH 3 –O 2 ) plasma treatment and found that the hydrophilicity of membrane was improved in comparison with pristine PSF membrane.…”

Section: Polysulfone Functionalized Membranes For Hemodialysismentioning

confidence: 99%

Functionalized Hemodialysis Polysulfone Membranes with Improved Hemocompatibility

Radu

Voicu

2022

Polymers

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The field of membrane materials is one of the most dynamic due to the continuously changing requirements regarding the selectivity and the upgradation of the materials developed with the constantly changing needs. Two membrane processes are essential at present, not for development, but for everyday life—desalination and hemodialysis. Hemodialysis has preserved life and increased life expectancy over the past 60–70 years for tens of millions of people with chronic kidney dysfunction. In addition to the challenges related to the efficiency and separative properties of the membranes, the biggest challenge remained and still remains the assurance of hemocompatibility—not affecting the blood during its recirculation outside the body for 4 h once every two days. This review presents the latest research carried out in the field of functionalization of polysulfone membranes (the most used polymer in the preparation of membranes for hemodialysis) with the purpose of increasing the hemocompatibility and efficiency of the separation process itself with a decreasing impact on the body.

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Section: Polysulfone Functionalized Membranes For Hemodialysismentioning

confidence: 99%

Functionalized Hemodialysis Polysulfone Membranes with Improved Hemocompatibility

Radu

Voicu

2022

Polymers

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“…Zheng, et al [81] compared different materials, i.e. acrylic acid with heparin (AA-Hep), 2-methacryloyloxyethyl phosphorylcholine (MPC), and collagen, to study their biocompatibility.…”

Section: Surface Modification Of Membrane Oxygenatormentioning

confidence: 99%

“…Membrane oxygenators are usually fabricated using polymeric materials, such as polysulfone [15], polyurethane [16], polypropylene [17], polyimide [18], and silicon [19][20][21][22]. Among these polymers, non-porous silicon-based hollow fiber is used in commercial ECMO systems due to its ability to avoid plasma leakage during the long time of extracorporeal circulation.…”

Section: Introductionmentioning

confidence: 99%

Membrane Oxygenator for Extracorporeal Blood Oxygenation

Ratnaningsih

Aryanti

Himma

et al. 2021

J. Eng. Technol. Sci.

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Extracorporeal blood oxygenation has become an alternative to supply O2 and remove CO2 from the bloodstream, especially when mechanical ventilation provides insufficient oxygenation. The use of a membrane oxygenator offers the advantage of lower airway pressure than a mechanical ventilator to deliver oxygen to the patient’s blood. However, research and development are still needed to find appropriate membrane materials, module configuration, and to optimize hydrodynamic conditions for achieving high efficient gas transfer and excellent biocompatibility of the membrane oxygenator. This review aims to provide a comprehensive description of the basic principle of the membrane oxygenator and its development. It also discusses the role and challenges in the use of membrane oxygenators for extracorporeal oxygenation on respiratory and cardiac failure patients.

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“…Moreover, they lead to increased mass-transfer coefficients of the required component from one phase to another and, consequently, to compact separation modules [3]. Gas-liquid membrane contactors are already widely used for various applications, including blood oxygenation [4,5], the removal of acid gases (CO 2 , H 2 S, SO 2 ) from gaseous media [6,7], the removal of dissolved gases from liquids [8,9], and the separation of saturated and unsaturated hydrocarbons [10].…”

Section: Introductionmentioning

confidence: 99%

Interphase Surface Stability in Liquid-Liquid Membrane Contactors Based on Track-Etched Membranes

et al. 2021

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A promising solution for the implementation of extraction processes is liquid–liquid membrane contactors. The transfer of the target component from one immiscible liquid to another is carried out inside membrane pores. For the first time, highly asymmetric track-etched membranes made of polyethylene terephthalate (PET) of the same thickness but with different pore diameters (12.5–19 nm on one side and hundreds of nanometers on the other side) were studied in the liquid–liquid membrane contactor. For analysis of the liquid–liquid interface stability, two systems widely diverging in the interfacial tension value were used: water–pentanol and water–hexadecane. The interface stability was investigated depending on the following process parameters: the porous structure, the location of the asymmetric membrane in the contactor, the velocities of liquids, and the pressure drop between them. It was shown that the stability of the interface increases with decreasing pore size. Furthermore, it is preferable to supply the aqueous phase from the side of the asymmetric membrane with the larger pore size. The asymmetry of the porous structure of the membrane makes it possible to increase the range of pressure drop values between the phases by at least two times (from 5 to 10 kPa), which does not lead to mutual dispersion of the liquids. The liquid–liquid contactor based on the asymmetric track-etched membranes allows for the extraction of impurities from the organic phase into the aqueous phase by using a 1% solution of acetone in hexadecane as an example.

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Surface modification of polysulfone hollow fiber membrane for extracorporeal membrane oxygenator using low‐temperature plasma treatment

Cited by 20 publications

References 34 publications

Functionalized Hemodialysis Polysulfone Membranes with Improved Hemocompatibility

Functionalized Hemodialysis Polysulfone Membranes with Improved Hemocompatibility

Membrane Oxygenator for Extracorporeal Blood Oxygenation

Interphase Surface Stability in Liquid-Liquid Membrane Contactors Based on Track-Etched Membranes

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