Surface Plasmon Resonance Instruments

Schasfoort, Richard B.M.

doi:10.1039/9781788010283-00060

Cited by 47 publications

(62 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Analyte-specific antibodies are immobilized onto the metal layer of the sensor chip, mounted onto a glass prism with an integrated flow cell that is then placed in the instrument. When polarized light shines through the prism, the light is reflected by the metal layer, resulting in an angle of incidence capable of inducing surface plasmon resonance and causing a dip in the reflected light intensity [136]. The refractive index near the metal surface will change as proteins are adsorbed onto the metal surface and the amount of adsorbed protein can then be determined.…”

Section: Methods For Food Allergen Detection Using a Smartphone Readomentioning

confidence: 99%

Consumer-friendly food allergen detection: moving towards smartphone-based immunoassays

2018

View full text Add to dashboard Cite

In this critical review, we provide a comprehensive overview of immunochemical food allergen assays and detectors in the context of their user-friendliness, through their connection to smartphones. Smartphone-based analysis is centered around citizen science, putting analysis into the hands of the consumer. Food allergies represent a significant worldwide health concern and consumers should be able to analyze their foods, whenever and wherever they are, for allergen presence. Owing to the need for a scientific background, traditional laboratory-based detection methods are generally unsuitable for the consumer. Therefore, it is important to develop simple, safe, and rapid assays that can be linked with smartphones as detectors to improve user accessibility. Smartphones make excellent detection systems because of their cameras, embedded flash functions, portability, connectivity, and affordability. Therefore, this review has summarized traditional laboratory-based methods for food allergen detection such as enzyme-linked-immunosorbent assay, flow cytometry, and surface plasmon resonance, and the potential to modernize these methods by interfacing them with a smartphone readout system, based on the aforementioned smartphone characteristics. This is the first review focusing on smartphone-based food-allergen detection methods designed with the intention of being consumer-friendly. Graphical abstractA smartphone-based food allergen detection system in three easy steps (1) sample preparation, (2) allergen detection on a smartphone using antibodies, which then transmits the data wirelessly, (3) analytical results sent straight to smartphone Electronic supplementary materialThe online version of this article (10.1007/s00216-018-0989-7) contains supplementary material, which is available to authorized users.

show abstract

Section: Methods For Food Allergen Detection Using a Smartphone Readomentioning

confidence: 99%

Consumer-friendly food allergen detection: moving towards smartphone-based immunoassays

2018

View full text Add to dashboard Cite

show abstract

“…SPR technique works are based on two types of configurations, namely Kretschman and otto. The technique allows for measurement of each bound molecule in a form of shift observed at the surface of the sensor 9 , 10 . Among the advantages of SPR biosensors are the small size, high-resolution detection, remote sensing feature, etc., making them useful for detection of biochemical molecules, particularly in environmental and clinical applications 11 .…”

Section: Introductionmentioning

confidence: 99%

Tunable infrared metamaterial-based biosensor for detection of hemoglobin and urine using phase change material

Patel

Parmar

Sorathiya

et al. 2021

Sci Rep

View full text Add to dashboard Cite

This paper reports about the outcomes from an investigation carried out on tunable biosensor for detection using infrared in the range of 1.5 µm and 1.65 µm. The biosensor is made of phase change material formed by different alloy combinations, Ge2Sb2Te5 (GST). The nature of GST allows for the material to change phase with changes in temperature, giving the tunable sensing property for biosensing application. Sensor built with amorphous GST (aGST) and crystalline GST (cGST) in different design structures were tested on different concentrations of biomolecules: hemoglobin (10 g/l, 20 g/l, 30 g/l and 40 g/l); and urine (0–1.5 mg/dL, 2.5 mg/dL, 5 mg/dL and 10 mg/dL). The tunable response observed from the tests demonstrates the potential application of the materials in the design of switching and sensing systems.

show abstract

“…When the target analyte is captured by the ligand, it causes a measurable signal. Various sensor surfaces with immobilized ligands are commercially available and/or can be custom designed and fabricated [ 56 ]. In general, plasmonic sensors are created of sensing elements that contain metal or metal-dielectric nanostructures supporting surface plasmons and recognition elements that can selectively bind a target analyte.…”

Section: Principle Of Sensorsmentioning

confidence: 99%

Plasmonic Sensors for Monitoring Biological and Chemical Threat Agents

2020

View full text Add to dashboard Cite

Sensors are excellent options owing to their ability to figure out a large number of problems and challenges in several areas, including homeland security, defense, medicine, pharmacology, industry, environment, agriculture, food safety, and so on. Plasmonic sensors are used as detection devices that have important properties, such as rapid recognition, real-time analysis, no need labels, sensitive and selective sensing, portability, and, more importantly, simplicity in identifying target analytes. This review summarizes the state-of-art molecular recognition of biological and chemical threat agents. For this purpose, the principle of the plasmonic sensor is briefly explained and then the use of plasmonic sensors in the monitoring of a broad range of biological and chemical threat agents is extensively discussed with different types of threats according to the latest literature. A conclusion and future perspectives are added at the end of the review.

show abstract

Surface Plasmon Resonance Instruments

Cited by 47 publications

References 32 publications

Consumer-friendly food allergen detection: moving towards smartphone-based immunoassays

Consumer-friendly food allergen detection: moving towards smartphone-based immunoassays

Tunable infrared metamaterial-based biosensor for detection of hemoglobin and urine using phase change material

Plasmonic Sensors for Monitoring Biological and Chemical Threat Agents

Contact Info

Product

Resources

About