Surface plasmon resonance sensor using polypyrrole-chitosan/graphene quantum dots layer for detection of sugar

Sadrolhosseini, Amir Reza; Rashid, Suraya Abdul; Jamaludin, Norhanisah; Noor, Ahmad Shukri Mohd; Isloor, Arun M.

doi:10.1088/2053-1591/ab0b7a

Cited by 23 publications

(9 citation statements)

References 43 publications

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“…As powerful analytical tools that have enjoyed widespread attention over the past two decades, SPR sensors have been developed in several configurations to detect several analytes. These sensors serve in different fields such as medical diagnostics [318][319][320][321][322], food quality [323,324], environmental protection [325][326][327][328][329][330][331] and others. SPR, a refractive index-based detection technique has emerged as a promising sensing platform for sensitive detection of NTs, especially DA due to its substantial advantages.…”

Section: Surface Plasmon Resonance Spectroscopymentioning

confidence: 99%

Recent Advances in Electrochemical and Optical Sensing of Dopamine

Eddin

Fen

2020

Sensors

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Nowadays, several neurological disorders and neurocrine tumours are associated with dopamine (DA) concentrations in various biological fluids. Highly accurate and ultrasensitive detection of DA levels in different biological samples in real-time can change and improve the quality of a patient’s life in addition to reducing the treatment cost. Therefore, the design and development of diagnostic tool for in vivo and in vitro monitoring of DA is of considerable clinical and pharmacological importance. In recent decades, a large number of techniques have been established for DA detection, including chromatography coupled to mass spectrometry, spectroscopic approaches, and electrochemical (EC) methods. These methods are effective, but most of them still have some drawbacks such as consuming time, effort, and money. Added to that, sometimes they need complex procedures to obtain good sensitivity and suffer from low selectivity due to interference from other biological species such as uric acid (UA) and ascorbic acid (AA). Advanced materials can offer remarkable opportunities to overcome drawbacks in conventional DA sensors. This review aims to explain challenges related to DA detection using different techniques, and to summarize and highlight recent advancements in materials used and approaches applied for several sensor surface modification for the monitoring of DA. Also, it focuses on the analytical features of the EC and optical-based sensing techniques available.

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Section: Surface Plasmon Resonance Spectroscopymentioning

confidence: 99%

Recent Advances in Electrochemical and Optical Sensing of Dopamine

Eddin

Fen

2020

Sensors

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“…Figure 30 outlines the general instrumentation that works on the SPR principle. In 2019, Sadrolhosseini et al developed a biosensor based on the principle of SPR, where polypyrrole-chitosan/GQDs was electrodeposited on a gold-coated glass chip [362]. The as-formed film was characterized by FE-SEM as well as XRD and the sensor could quantify glucose, fructose as well as sucrose.…”

Section: Photoelectrochemical and Miscellaneous Gqd Sensors In Biomedmentioning

confidence: 99%

Applications of Graphene Quantum Dots in Biomedical Sensors

Mansuriya

Altıntaş

2020

Sensors

190

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Due to the proliferative cancer rates, cardiovascular diseases, neurodegenerative disorders, autoimmune diseases and a plethora of infections across the globe, it is essential to introduce strategies that can rapidly and specifically detect the ultralow concentrations of relevant biomarkers, pathogens, toxins and pharmaceuticals in biological matrices. Considering these pathophysiologies, various research works have become necessary to fabricate biosensors for their early diagnosis and treatment, using nanomaterials like quantum dots (QDs). These nanomaterials effectively ameliorate the sensor performance with respect to their reproducibility, selectivity as well as sensitivity. In particular, graphene quantum dots (GQDs), which are ideally graphene fragments of nanometer size, constitute discrete features such as acting as attractive fluorophores and excellent electro-catalysts owing to their photo-stability, water-solubility, biocompatibility, non-toxicity and lucrativeness that make them favorable candidates for a wide range of novel biomedical applications. Herein, we reviewed about 300 biomedical studies reported over the last five years which entail the state of art as well as some pioneering ideas with respect to the prominent role of GQDs, especially in the development of optical, electrochemical and photoelectrochemical biosensors. Additionally, we outline the ideal properties of GQDs, their eclectic methods of synthesis, and the general principle behind several biosensing techniques.

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“…Figure 1 shows the SPR setup with a high index prism based on angular modulation, and the variation of laser beam intensity was detected at a different angle using a silicon photodetector. The PPy-Chi-BaFe 2 O 4 composite layer was deposited on the gold side of the glass slide, and it was attached to a high index prism (SF52, Foctek) using the index matching gel (F-IMF-105, Newport, USA) [12,24,25]. The prism was placed on a precision rotation stage, and the fluid holder was contacted to the sensing layer using an O-ring.…”

Section: Surface Plasmon Resonance Setupmentioning

confidence: 99%

“…The optical method is an interesting technique to evaluate chemical and biochemical properties [7]. Hence, the detection and measurement of low concentrations of glucose, fructose, and sucrose were carried out using a laser interferometer [8] Ultraviolet-visible (UV-Vis) absorption spectroscopy, fluorescence spectroscopy, the optical polarization properties of medium and heterodyne polarimetry [9,10], reflected THz radiation [11], and a surface plasmon resonance sensor [12][13][14]. Recently, glucose biosensors have been presented based on enzymatic catalysts in three versions of enzymatic glucose biosensors [15].…”

Section: Introductionmentioning

confidence: 99%

Surface Plasmon Resonance Sensor Based on Polypyrrole–Chitosan–BaFe2O4 Nanocomposite Layer to Detect the Sugar

Sadrolhosseini

Nia²,

Naseri

et al. 2020

Applied Sciences

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The surface plasmon resonance sensor was used to detect and measure low concentrations of sugar. A polypyrrole–chitosan–BaFe2O4 nanocomposite layer was prepared to improve the surface of the gold layer for the detection of glucose, fructose, and sucrose using the surface plasmon resonance technique. The polypyrrole–chitosan–BaFe2O4 was synthesized using the electrodeposition method in different thicknesses. The functional group, crystal structure, and morphology of the layer were investigated with Fourier transform infrared spectroscopy, X-ray diffraction technique, and field emission electron microscopy. Consequently, the BaFe2O4 was scattered on the surface of the polymer, and the affinity of polypyrrole–chitosan–BaFe2O4 to bond with glucose is higher than that for the other sugars. The sensor limit was 0.005 ppm.

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Surface plasmon resonance sensor using polypyrrole-chitosan/graphene quantum dots layer for detection of sugar

Cited by 23 publications

References 43 publications

Recent Advances in Electrochemical and Optical Sensing of Dopamine

Recent Advances in Electrochemical and Optical Sensing of Dopamine

Applications of Graphene Quantum Dots in Biomedical Sensors

Surface Plasmon Resonance Sensor Based on Polypyrrole–Chitosan–BaFe2O4 Nanocomposite Layer to Detect the Sugar

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