We study a holographic model which exhibits a quantum phase transition from the strongly interacting Weyl semimetal phase to an insulating phase. In the holographic insulating phase there is a hard gap in the real part of frequency dependent diagonal conductivities. However, the anomalous Hall conductivity is nonzero at zero frequency, indicting that it is a Chern insulator. This holographic quantum phase transition is always of first order, signified by a discontinuous anomalous Hall conductivity at the phase transition, in contrast to the very continuous holographic Weyl semimetal/trivial semimetal phase transition. Our work reveals the novel phase structure of strongly interacting Weyl semimetal.. The independent parameters are T, f 1 , h 1 , A z1 , φ 1 . With the above scaling symmetries, we only have two free parameters, which correspond to M/b, T /b in the dual field theory.