“…This severely restricts the size and complexity of models that can be used for control. To this end, key drivers for efficient operation of such intensified systems are novel sensors and actuators [101][102][103][104][105][106][107][108], reduced-order model-based controllers [86,109] and faster control algorithms (such as explicit MPC) [38,39,110]. The thermodynamic domain of intensification involves use of alternate driving forces or energy sources, resulting in spinning disc reactors, microwave assisted reactors, sono-crystallizers, etc.…”