2017
DOI: 10.1002/admi.201700929
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Surface Wrinkling and Porosity of Polymer Particles toward Biological and Biomedical Applications

Abstract: Polymer particles are promising particulate materials for renowned biomedical applications such as targeted drug delivery, tissue engineering and biosensing. Surface properties of the polymer particles are of key importance for biomedical applications because they directly interact with biological systems. Particularly, wrinkled as well as porous surfaces possess an enhanced ability for cell attachment without any additional chemical modification. Therefore, a key objective is to fabricate the particles with d… Show more

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Cited by 26 publications
(30 citation statements)
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“…From literature, 67,68 it is hypothesized that the unique surface morphology of the footpad is not only responsive to interactions with external stimuli but also has great potential for biosensing due to its ability to adhere with living cells or tissues. Theories were developed to support the hypothesis, yet no experiment validations were presented.…”
Section: Biocompatibility Of Robotmentioning
confidence: 99%
“…From literature, 67,68 it is hypothesized that the unique surface morphology of the footpad is not only responsive to interactions with external stimuli but also has great potential for biosensing due to its ability to adhere with living cells or tissues. Theories were developed to support the hypothesis, yet no experiment validations were presented.…”
Section: Biocompatibility Of Robotmentioning
confidence: 99%
“…By microfluidic photopolymerization, surface fabrication of the microscale particles such as wrinkled and porous surface can be fabricated which has a high potential for some renowned biomedical applications such as tissue regeneration and surface‐enhanced Raman scattering based molecular sensing. [ 160 ]…”
Section: Nano–micro Multiscale Assemblymentioning
confidence: 99%
“…The wrinkling and buckling of thin films at all scales show wide applications in biology, 28,29 tunable diffraction gratings, 30 modern metrology methods, 31,32 and soft and stretchable electronics. 3335 Especially the wrinkling and buckling of 2D nanofilms could extend the conventional planar structures into 3D buckled nanostructures while keeping the original excellent material properties of 2D nanofilms and even showing some innovative material properties.…”
Section: Introductionmentioning
confidence: 99%