Surfactant assisted nisin loaded chitosan-carageenan nanocapsule synthesis for controlling food pathogens

Chopra, Meenu; Kaur, Pawan; Bernela, Manju; Thakur, Rajesh

doi:10.1016/j.foodcont.2013.09.024

Cited by 107 publications

(46 citation statements)

References 17 publications

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“…The application of foodgrade biopolymers for encapsulating, protecting and delivery of antimicrobial peptides is an alternative way. Nisin loaded-micro or nanocapsules were prepared using chitosan/carrageenan (Chopra, Kaur, Bernela, & Thakur, 2014) chitosan/alginate (Zohri et al, 2013), alginate/cellulose (Huq, Riedl, Bouchard, Salmieri, & Lacroix, 2014), alginate/pectin (Khaksar et al, 2014) and alginate/ guar gum (Narsaiah, Jha, Wilson, Mandge, & Manikantan, 2014) biopolymer systems.…”

Section: Introductionmentioning

confidence: 99%

Nisin-loaded pectin nanoparticles for food preservation

et al. 2016

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Section: Introductionmentioning

confidence: 99%

Nisin-loaded pectin nanoparticles for food preservation

et al. 2016

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“…They interacted differently with HA receptors (e.g. CD44) and displayed different kinetics and mechanism of the release [ 41 ]. Another strategy to modulate the bioactivity of chitosan-based nanocomposites was irradiation by electron beam of the nanocomposites made using by-products of the sea (chitosan and fi sh gelatin) or to make fi lms encapsulating natural antioxidants (quercetin, tyrosol, ferulic acid).…”

Section: Loading Active Agents Into Nanochitosanmentioning

confidence: 99%

Nanochitosan and the Skin

Leonida

Kumar

2016

SpringerBriefs in Bioengineering

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Chitosan is a non-toxic, biodegradable, polycationic polysaccharide, easily obtained from the naturally abundant chitin from the exoskeleton of crustaceans (Fig. 9.1 ) through deacetylation (partial, typically 66-95 %) and partial depolymerization (less extensive). It is a polymeric 2-amino-2-deoxy-β-D-glucan formed through 1→4 glycosidic linkages. The interest in chitosan as delivery vehicle for active species was generated by the knowledge that it is broken down by the enzyme lysozyme in the human body releasing harmless amino sugars [ 1 ], hence biocompatible. The rate and extent of its biodegradability depends on its degree of deacetylation (DD), slower for higher DD values [ 2 ].Great interest in this semisynthetic biopolymer obtained from renewable sources (chitin) stems from its remarkable properties : adhesivity, antimicrobial and antifungal effect, immunity enhancing effect, chelating effect, fi lm and gel forming abilities. As such it found applications in pharmaceuticals, as drug delivery vehicle or vaccine carrier, in biotechnology as gene delivery system, in textiles, spun into fi bers or as a coating, in dentistry, in removal of heavy metals from waste waters, as preservative in the food industry, and many others.Chitosan was found active against both gram positive and gram negative bacteria [ 3 -5 ], and fungi [ 6 ]. This, together with its adhesivity, made it interesting for skin applications as well. High molecular weight chitosans have been found more active against gram positive bacteria while low molecular weight ones were more active against gram negative species [ 7 ]. Positively charged chitosan binds to the negatively charged bacterial membrane, triggering agglutination and/or an increase in its permeability, resulting in leakage of cellular components. The fact that chitosan can chelate metals and thereby contributes to inhibiting some enzymatic activities is also part of its biological activity.Being nontoxic and biocompatible , chitosan has been approved by the FDA for use in wound dressings [ 8 ]. As a wound healing biodegradable material chitosan is

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“…Release kinetics monitored in vitro , over 2 weeks was slow and sustained. The nanocapsules showed good antimicrobial activity against P. aeruginosa and several gram positive bacteria [ 48 ].…”

Section: Bacteriocins Delivered In Nanostructuresmentioning

confidence: 99%