Surfactant catalyzed convenient and greener synthesis of tetrahydrobenzo[a]xanthene-11-ones at ambient temperature

Abstract

SummaryAn efficient and greener protocol for the synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-one using tetradecyltrimethylammonium bromide (TTAB) at room temperature in water is described.

H4SiW12O40 Catalyzed One‐Pot Synthesis of 12‐Aryl‐8,9,10,12‐tetrahydrobenzo[a] Xanthen‐11‐ones Under Solvent‐Free Conditions

“…The solid product was purified by recrystallization from EtOH to afford the pure product. All compounds are known and their physical and spectroscopic data were in good agreement with those of authentic samples [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] .…”

Iodocyclization of Diallyl-Dihydroxy Naphthalenes Using <i>N</i>-Iodosuccinimide vs Molecular Iodine in Aqueous Micelle

“…Surfactants contain both hydrophobic groups (their lypophilic tails called micelles) and hydrophobic groups (their heads). A large volume of literature is available on the use of surfactants as cosolvents for carrying out a variety of reactions in aqueous media [37][38][39][40][41][42][43][44]. The surfactants (cationic, anionic and neutral) form micelles in protic sovents especially in water.…”

Natural Organic Acid as Green Catalyst for Xanthenones Synthesis: Methodology, Mechanism and Calcium Channel Blocking Activity

“…6 The literature describes the synthesis of xanthenones via a multicomponent reaction using a phenolic compound, an aldehyde, and a cyclic 1,3-dicarbonyl compound. 7 Many Lewis or Brönsted acids may be used as catalysts: calixarenes, 3 ceric ammonium nitrate, 4 polyethyleneglycol bound sulfonic acid, 5 Hy zeolite, 6 triflate proline, 8 tetrabutyl ammonium fluoride, 9 tri-methyl tetradecyl ammonium bromide, 10 sulfamic acid, 11 p-toluenesulfonic acid, 12 triphenylphosphinem-sulfonate/carbon tetrabromide, 13 phosphorus(V) oxide, cumbersome product isolation procedures. 16 They also use expensive and/or detrimental metal precursors, 14,15,22 toxic catalysts, 11,14 and toxic organic solvents to perform the reaction or purify the product.…”