Surfactants, skin cleansing protagonists

Corazza, Monica; Lauriola, Maria Michela; Zappaterra, Mario; Bianchi, Anna; Virgili, Annarosa

doi:10.1111/j.1468-3083.2009.03349.x

Cited by 76 publications

(72 citation statements)

References 28 publications

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“…On the one hand, the irritant effects of skin cleansing products depend on how intensively (mechanically) or how long the cleansing product must act on the skin in order to cleanse it in the desired way. On the other hand, the irritant potency is dependent on the type of chemical detergent employed (anionic, cationic, amphoteric, non‐ionic), respectively their combined use . For some individual substances used in skin cleansing products, safety assessments have been conducted .…”

Section: Occupational Skin Products – Safety Assessment and Undesirabmentioning

confidence: 99%

S1 guideline on occupational skin products: protective creams, skin cleansers, skin care products (ICD 10: L23, L24) – short version

Fartasch

Diepgen

Drexler

et al. 2015

J Deutsche Derma Gesell

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Job-related hand dermatitis heads up the list of reported occupational diseases. So-called skin products - understood to mean protective creams, skin cleansers and skin care products - are used for the primary and secondary prevention of job- related hand dermatitis. In the interests of evidence-based medicine, the only preventive measures and/or occupational skin products that should be used are those whose potential uses and efficacy are underpinned by scientific research. To this end, the Arbeitsgemeinschaft für Berufs- und Umweltdermatologie e.V. (Working Group for Occupational and Environmental Dermatology, ABD) of the DDG (German Dermatological Society) and the Deutsche Gesellschaft für Arbeits- und Umweltmedizin (German Society for Occupational and Environmental Medicine, DGAUM) have summed up the latest scientific findings and recommendations in the updated guideline. The benefit of the combined application of protective creams and skin care products in the primary and secondary prevention of work-related contact dermatitis has been widely confirmed by recent clinical-epidemiological studies. The guideline clearly explains the necessity of demonstrating the efficacy of protective creams and cleansing products by means of in vivo methods in the sense of repetitive applications. Transferable standardised testing systems designed to examine the irritation potential and thus the compatibility of occupational skin cleansers and the reduction of irritation by protective skin creams have now been developed and validated by multicentre studies for skin protection creams and cleansers. The status of the current assessment of the safety of occupational skin products is also summarised.

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Section: Occupational Skin Products – Safety Assessment and Undesirabmentioning

confidence: 99%

S1 guideline on occupational skin products: protective creams, skin cleansers, skin care products (ICD 10: L23, L24) – short version

Fartasch

Diepgen

Drexler

et al. 2015

J Deutsche Derma Gesell

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“…[26][27][28] The perfumes chosen cover a very broad range of molecular structures and the log P values change from 0.27 to 4.46. Our goal is to relate the differences in the aggregation behaviour of the surfactant to the molecular structures of perfumes, and improve the understanding of the effect of perfume molecules on the self-assembly of the surfactant.…”

Section: Introductionmentioning

confidence: 99%

Modulation of partition and localization of perfume molecules in sodium dodecyl sulfate micelles

Fan

Tang²,

Strand³

et al. 2016

Soft Matter

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The influence of perfume molecules on the self-assembly of the anionic surfactant sodium dodecyl sulfate (SDS) and their localization in SDS micelles have been investigated by ζ potential, small angle X-ray scattering (SAXS), one- and two-dimensional NMR and isothermal titration microcalorimetry (ITC). A broad range of perfume molecules varying in octanol/water partition coefficients P are employed. The results indicate that the surface charge, size and aggregation number of the SDS micelles strongly depend on the hydrophobicity/hydrophilicity degree of perfume molecules. Three distinct regions along the log P values are identified. Hydrophilic perfumes (log P < 2.0) partially incorporate into the SDS micelles and do not lead to micelle swelling, whereas hydrophobic perfumes (log P > 3.5) are solubilized close to the end of the hydrophobic chains in the SDS micelles and enlarge the micelles with higher ζ potential and a larger aggregation number. The incorporated fraction and micelle properties show increasing tendency for the perfumes in the intermediate log P region (2.0 < log P < 3.5). Besides, the molecular conformation of perfume molecules also affects these properties. The perfumes with a linear chain structure or an aromatic group can penetrate into the palisade layer and closely pack with the SDS molecules. Furthermore, the thermodynamic parameters obtained from ITC show that the binding of the perfumes in the intermediate log P region is more spontaneous than those in the other two log P regions, and the micellization of SDS with the perfumes is driven by entropy.

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“…Detergents can be categorized according to the charge present in the hydrophilic head (after dissociation in aqueous solution) into four primary groups: anionic, cationic, amphoteric (dual charge) and nonionic (Corazza et al, 2010). (Takahashi et al, 2011).…”

Section: Discussionmentioning

confidence: 99%