Surgery for Gastrointestinal Stromal Tumors of the Stomach

Silberhumer, Gerd R.; Hufschmid, Martin; Wrba, Fritz; Gyoeri, Georg; Schoppmann, Sebastian F.; Tribl, Barbara; Wenzl, E.; Prager, Gerhard; Laengle, Friedrich; Zacherl, Johannes

doi:10.1007/s11605-009-0872-0

Cited by 54 publications

(46 citation statements)

References 33 publications

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“…In this report, we analyzed the results of a homogenous population of 151 patients with primary GIST treated by the GISTologist Study Groupduringthepast11years.Thedisease-freesurvivalrate forall151patientsinthisstudywas77%at5years,whichis similar to the results of Silberhumer et al [5] who reported 85%survivalat5yearsinagroupof63patients.…”

Section: Discussionsupporting

confidence: 89%

Microscopic Margins of Resection Influence Primary Gastrointestinal Stromal Tumor Survival

Catena

Battista²,

Ansaloni³

et al. 2012

Oncol Res Treat

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Background: Primary gastrointestinal stromal tumors (GISTs) are stromal tumors that arise from the gastrointestinal tract. Both surgical resection and molecular therapy are crucial in the treatment of these tumors. This study analyzes the outcomes of 151 patients with GIST treated at 3 institutions. These institutions comprise the GISTologist Study Group and provided follow-up data. Patients and Methods: 151 patients with primary GIST were admitted and treated at the St. Orsola-Malpighi University Hospital in Bologna, Italy, the Catholic University Hospital in Rome, Italy, and the Modena University Hospital and National Cancer Institute in Naples, Italy, over the past 11 years. Patient data as well as tumor and therapy variables were studied to identify factors predicting survival with a focus on the microscopic margins of resection. Results: All 151 patients had primary disease without metastasis and underwent complete resection of gross disease. The 5-year disease-free survival rate was 77%. Disease-free survival was predicted by tumor size, mitotic count, and margins of resection. Recurrence of disease after resection was predominantly intra-abdominal. Conclusions: Tumor size, mitotic count, and microscopic margins of resection predict disease-free survival in patients with primary GIST.

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Section: Discussionsupporting

confidence: 89%

Microscopic Margins of Resection Influence Primary Gastrointestinal Stromal Tumor Survival

Catena

Battista²,

Ansaloni³

et al. 2012

Oncol Res Treat

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show abstract

“…3 Although the majority of SETs are considered benign, some do have malignant potential. 4,5 In the present study, the prevalence of gastric SETs was 1.7%, and that increased with age. In Korea, the national healthcare program recommends gastroscopy every two years irrespective of the presence of symptoms.…”

Section: Discussionsupporting

confidence: 48%

Prevalence of Gastric Subepithelial Tumors in Korea: A Single Center Experience

Lee

Ahn

et al. 2015

Korean J Gastroenterol

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“…However, there are limited data comparing traditional open versus laparoscopic resection of these tumors [13][14][15][16][17][18][19]. The aim of the current study was to assess the feasibility and safety of minimally invasive surgery for treating gastric stromal tumors and to compare laparoscopic to open surgery in the management of these neoplasms.…”

mentioning

confidence: 99%

Laparoscopic versus open resection of gastrointestinal stromal tumors of the stomach

Vogelaere

Hoorens

Haentjens³

et al. 2012

Surg Endosc

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Surgery for Gastrointestinal Stromal Tumors of the Stomach

Abstract: Histologically proven complete resection is an effective treatment for gastric GIST. Laparoscopic procedures were carried out successfully in selected patients.

Cited by 54 publications

References 33 publications

Microscopic Margins of Resection Influence Primary Gastrointestinal Stromal Tumor Survival

Microscopic Margins of Resection Influence Primary Gastrointestinal Stromal Tumor Survival

Prevalence of Gastric Subepithelial Tumors in Korea: A Single Center Experience

Laparoscopic versus open resection of gastrointestinal stromal tumors of the stomach

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