Surgery for Hilar cholangiocarcinoma: the Newcastle upon Tyne Liver Unit experience

Malik, Arshi; Robinson, Stuart; French, Jeremy; Sen, Gourab; Hammond, John S.; White, Steven A.; Manas, Derek

doi:10.1007/s10353-019-0599-4

Cited by 2 publications

(2 citation statements)

References 34 publications

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“…They reported that survival was longer in patients with extended left hepatectomy and en bloc resection of the caudate lobe. They also say that extended left hepatectomy is an independent risk factor for survival [21]. One of the most feared complications of hepaticojejunostomy is bile leakage (0.4-8%) [9,22,23].…”

Section: Discussionmentioning

confidence: 99%

“…Survival rates of the series with palliative resection have been reported to vary between 10 and 28 months. In contrast, in the series with biliary bypass or photodynamic therapy (PDT) in some cases, survival can change between 5.6 and 16 months [8,21,29]. Survival was reported between 1.4 and 8.7 months in patients with inoperable hilar cholangiocarcinoma who performed the endoscopic or percutaneous interventional procedure.…”

Section: Discussionmentioning

confidence: 99%

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The Role of Portoenterostomy with Aggressive Hilar Dissection in Biliary Tract Tumors: Report of Case Series and Review of the Literature

et al. 2020

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Hepaticojejunostomy is a challenging and complex procedure to be done with confidence in conditions that contain a large number of segmental bile ducts. Portoenterostomy can be defined as the joining of multiple bile ducts into a single cavity using segmenter bile duct ends, stents, and surrounding connective tissues. During surgery, in cases with advanced stage biliary tract tumors that cannot be performed hepatectomy, after aggressive dissections to provide a negative surgical margin, a large number of segmental bile ducts can be revealed and needs to ensure the continuity of bile flow. Here, our clinical series of portoenterostomy (PE) in which we applied in patients who had aggressive hilar dissection and resection for hilar cholangiocarcinomas and biliary tract tumors were discussed. The study included 15 patients who underwent PE for biliary tract tumors and hilar cholangiocarcinomas between 2015 and 2019. Six of the patients had a tumor-negative surgical margin, with a mean follow-up of 14.4 months (range 2 to 28 months). Nine of the patients had a tumorpositive surgical margin, with a mean follow-up of 7.7 months (range 2 to 17 months). Portoenterostomy instead of hepaticojejunostomy in small and multiple biliary radicles and bile duct cancers has been successfully performed in 15 patients of bile duct cancer and Klatskin tumor. In the presence of active inflammation, fibrosis, major bile duct trauma, and thin bile duct radicles, this method, which is described in detail, provides an excellent salvage surgical procedure with less morbidity.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The Role of Portoenterostomy with Aggressive Hilar Dissection in Biliary Tract Tumors: Report of Case Series and Review of the Literature

et al. 2020

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Long-term morbidity after surgery for perihilar cholangiocarcinoma: A cohort study

et al. 2022

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Surgery for Hilar cholangiocarcinoma: the Newcastle upon Tyne Liver Unit experience

Abstract: Background Hilar cholangiocarcinoma (HCCA) arises from the confluence of the common hepatic duct and has a poor prognosis. If resectable, an extended left (eLH) or right hemihepatectomy (eRH) is usually required to provide oncological clearance. We reviewed

Cited by 2 publications

References 34 publications

The Role of Portoenterostomy with Aggressive Hilar Dissection in Biliary Tract Tumors: Report of Case Series and Review of the Literature

The Role of Portoenterostomy with Aggressive Hilar Dissection in Biliary Tract Tumors: Report of Case Series and Review of the Literature

Long-term morbidity after surgery for perihilar cholangiocarcinoma: A cohort study

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