Surgery for prosthetic valve obstruction. A single center study of 136 patients

Roudaut, R.; Roques, X.; Lafitte, Stéphane; Choukroun, Emmanuel; Laborde, Nadine; Madona, Francesco; Deville, Claude; Baudet, E

doi:10.1016/s1010-7940(03)00568-2

Cited by 51 publications

(36 citation statements)

References 18 publications

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“…However, medical treatment alone yielded even worse results. 7,11,16,17,21) In our series, the preoperative mortality rate was 7.1% in patients with NYHA functional classes II -III, and 31.3% with NYHA functional class IV. The difference in the mortality rate was rather high, reflecting mostly the seriousness of their preoperative functional capacity.…”

Section: Discussionmentioning

confidence: 61%

“…According to AHA recommendations, surgery is the preferred treatment for left-sided PVT. [16][17][18] Many authors recommend against using thrombolytic therapy (TT) in patients with left heart prostheses, as it carries a high risk of precipitating cerebral or peripheral embolism and the rethrombosis rate is higher. 7,19,20) Despite the fact patients in functional classes I-III have an operative mortality rate of 4.7%, which is similar to that of primary valve replacement, the surgical treatment of PVT in NYHA functional class IV has been associated with higher mortality (35 to 55%).…”

Section: Discussionmentioning

confidence: 99%

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Surgical Treatment of Left-sided Prosthetic Valve Thrombosis: Short and Long-term Results

Ozkokeli¹,

Sensoz²,

Ateş³

et al. 2005

Int. Heart J.

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SUMMARYWe report a single center experience of surgical treatment of 30 cases of left-sided prosthetic valve thrombosis (PVT). In our series, a diagnosis of PVT was established based on clinical and echocardiographic examinations. Thrombosis was the major etiologic factor in 25 patients (83.3%), while 22 of 25 patients (88%) had a subtherapeutic anticoagulation level. The early hospital mortality rate was 7.1% in patients with New York Heart Association (NYHA) functional classes II -III, and 31.3% in NYHA functional class IV. The median interval from the surgical procedure to follow-up for these patients was 29. Prosthetic valve thrombosis (PVT) is a rare but life-threatening condition. The incidence of PVT ranges from 0.03 to 4.3% patient-years, depending on the generation and the biocompabilities of the prosthesis used, the location of the valve, and inadequate or discontinued anticoagulation therapy.1, 2) Surgical mortality increases from 2% to 4% in low-risk groups to 37% to 54% in high-risk groups. [3][4][5] We report a single center experience of surgical treatment of 30 cases of leftsided PVT in order to better analyze the factors influencing success, determining operative mortality, and long-term survival.From the

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Section: Discussionmentioning

confidence: 61%

Section: Discussionmentioning

confidence: 99%

Surgical Treatment of Left-sided Prosthetic Valve Thrombosis: Short and Long-term Results

Ozkokeli¹,

Sensoz²,

Ateş³

et al. 2005

Int. Heart J.

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“…Choice of therapeutics: In our series, mechanical valve replacement is often performed: Mitral valve replacement in 113 patients (36 bioprothesis), Thrombectomy in 15 patients, Aortic valve replacement in 05 Patients, Tricuspid surgery in 02 Patients. Thrombectomy was the therapeutic choice despite the risk of rethrombosis, a risk that was raised in Roudaut's publication [5].…”

Section: Choice Of Therapymentioning

confidence: 99%

“…Others propose it in the event of signs of heart failure or in the absence of a surgical center: lower mortality/surgery [7][8][9][10][11]. 6) Right thrombosis: thrombolysis; Left thrombosis: surgery especially in case of chronic obstruction or left thrombosis [5]. Fibrinolysis is proposed in case of critical condition associated with recent obstruction in case of emergency surgery or in case of contraindication to surgery (low flow, redux, respiratory insufficiency) [5].…”

Section: Choice Of Therapymentioning

confidence: 99%

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Prosthetic Valve Thrombosis: About 205 Patients

Boukarroucha¹,

Massikh²,

S³

et al. 2017

J Cardiovasc Dis Diagn

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Background: The prosthetic heart valve thrombosis (PVT) is a life-threatening complication of mechanical valve prosthesis. It can be attributed more frequently to inadequate anticoagulant therapy. In the aortic and mitral position, reported incidences vary widely from 0.5% to 6% per patient-year, and are highest in the mitral position and up to 20% in tricuspid valve prosthesis. Medical therapy (Thrombolysis) has emerged as an alternative therapy in high-risk surgical patients, considering that surgical prosthetic valve replacement is related to significant operative morbidity and mortality rates. The purpose of this study is to present a single-center experience of 205 consecutive patients hospitalized between 2000 and 2016.

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Intra‐atrial tissue plasminogen activator infusion for prosthetic valve thrombosis

Seltzer

Reed

Siwik

2005

Cathet Cardio Intervent

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Thrombosis is a well-known and life-threatening complication of prosthetic mechanical valves. Therapy typically requires medical thrombolysis or surgical thrombectomy/valve replacement. We report the case of a thrombosed atrioventricular valve in a young boy with complex congenital heart disease, which was successfully treated with direct intra-atrial infusion of recombinant tissue plasminogen activator after failed attempts at systemic therapy. We present this treatment as an alternative to conventional medical therapy.

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Surgery for prosthetic valve obstruction. A single center study of 136 patients

Abstract: From this experience, it can be concluded that for most PHVO, early operation is currently effective and safe, especially in patients in stable hemodynamic condition preoperatively.

Cited by 51 publications

References 18 publications

Surgical Treatment of Left-sided Prosthetic Valve Thrombosis: Short and Long-term Results

Surgical Treatment of Left-sided Prosthetic Valve Thrombosis: Short and Long-term Results

Prosthetic Valve Thrombosis: About 205 Patients

Intra‐atrial tissue plasminogen activator infusion for prosthetic valve thrombosis

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