Surgery for rotator cuff tears

Karjalainen, Teemu; Jain, Nitin B.; Heikkinen, Juuso; Johnston, Renea V; Page, Cristina M; Buchbinder, Rachelle

doi:10.1002/14651858.cd013502

Cited by 67 publications

(94 citation statements)

References 103 publications

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“…If asymmetry in the funnel plot was detected, we planned to review the characteristics of the trials to assess whether the asymmetry was likely due to publication bias or other factors such as methodological or clinical heterogeneity of the trials. To assess outcome reporting bias, we compared the outcomes specified in trial protocols with the outcomes reported in the corresponding trial publications; if trial protocols were unavailable, we compared the outcomes reported in the methods and results sections of the trial publications.”187…”

Section: Reporting Bias Assessmentmentioning

confidence: 99%

“…“Compared with non-operative treatment, low-certainty evidence indicates surgery (repair with subacromial decompression) may have little or no effect on function at 12 months. The evidence was downgraded two steps, once for bias and once for imprecision—the 95% CIs overlap minimal important difference in favour of surgery at this time point.” A summary of findings table presents the same information as the text above, with footnotes explaining judgments 187…”

Section: Certainty Of Evidencementioning

confidence: 99%

“…The evidence was downgraded two steps, once for bias and once for imprecision-the 95% CIs overlap minimal important difference in favour of surgery at this time point." A summary of findings table presents the same information as the text above, with footnotes explaining judgments 187. BMJ: first published as 10.1136/bmj.n160 on 29 March 2021.…”

mentioning

confidence: 99%

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PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews

Page

Moher

Bossuyt

et al. 2021

BMJ

5,359

2,786

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The PRISMA 2020 statement includes a checklist of 27 items to guide reporting of systematic reviews In this article we explain why reporting of each item is recommended, present bullet points that detail the reporting recommendations, and present examples from published reviews We hope that uptake of the PRISMA 2020 statement will lead to more transparent, complete, and accurate reporting of systematic reviews, thus facilitating evidence based decision making on 15 April 2021 by guest. Protected by copyright.

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Section: Reporting Bias Assessmentmentioning

confidence: 99%

Section: Certainty Of Evidencementioning

confidence: 99%

See 1 more Smart Citation

PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews

Page

Moher

Bossuyt

et al. 2021

BMJ

5,359

2,786

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“…Rotator cuff tear is a common shoulder disease with an incidence of more than 20% that frequently requires surgical reconstruction 1 , 2 . The current surgical approaches to repair torn rotator cuff tendons have unacceptably low success ratios 3 . Failure is ascribed to a lack of functional enthesis structure, consisting of tendon, non-calcified fibrocartilage, calcified fibrocartilage, and bone, and formation of fibrovascular scar tissue with inferior mechanical properties 4 .…”

Section: Introductionmentioning

confidence: 99%

Synergistic enhancement of tendon-to-bone healing via anti-inflammatory and pro-differentiation effects caused by sustained release of Mg²⁺/curcumin from injectable self-healing hydrogels

Chen¹,

Liang²,

Zhang³

et al. 2021

Theranostics

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Poor healing response after rotator cuff reconstruction is multifactorial, with the inflammatory microenvironment and deficiency of stem cell differentiation factors at the lesion site being most relevant. However, there is a lack of effective tissue engineering strategies that can simultaneously exert anti-inflammatory and pro-differentiation effects to promote rotator cuff healing. Methods: In this study, we synthesized and characterized a novel active drug delivery vector that successfully overcame the challenge of simultaneous high-efficiency loading and controlled release of Mg 2+ and curcumin. The anti-inflammatory and pro-differentiation effects of the composite hydrogel were evaluated in vitro and in vivo . Moreover, healing of the rotator cuff tendon-to-bone interface was studied by histology, immunofluorescence, and biomechanical tests. Results: The composite hydrogel exhibited excellent biocompatibility and injectability, good adhesiveness, and rapid self-healing. The released curcumin showed obvious anti-inflammatory and antioxidation effects, which protected stem cells and tendon matrix. Furthermore, released Mg 2+ promoted stem cell aggregation and chondrogenesis. Moreover, biomechanical tests and histological results of a rat rotator cuff tear model at 8 weeks after surgery indicated that the composite hydrogel significantly enhanced tendon-to-bone healing. Conclusions: The composite hydrogel mediated sustained in situ release of curcumin and Mg 2+ to effectively promote rotator cuff tendon-to-bone healing via anti-inflammatory and pro-differentiation effects. Therefore, this composite hydrogel offers significant promise for rotator cuff repair.

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“…For early-stage impingement, conservative multimodal treatment is the most preferred option. On the other hand, for stage , stage impingement, and rotator cuff tears, shoulder arthroscopic surgery (including arthroscopic acromioplasty or/and rotator cuff repair) is an effective and minimally invasive treatment [3,4]. Although little visible blood loss in minimally invasive surgeries is well documented, postoperative hemoglobin (Hb) or hematocrit (Hct) of patients undergoing those surgeries are found to be maintained at lower levels than the preoperative [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Hidden Blood Loss and Factors in Shoulder Arthroscopy Surgery: A Review of 59 Patients

Jiangbo

Jin

Fang

et al. 2021

Preprint

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Purpose: Subacromial impingement syndrome (SIS) and its related rotator cuff tears are the most important cause of shoulder joint pain, which has recently received greater attention. Arthroscopy is a safe, effective, and minimally invasive procedure for the treatment of stage Ⅱ or Ⅲ SIS. Previous studies have reported that little blood loss usually occurs during this procedure. However, significant perioperative hidden blood loss (HBL) is often overlooked. In this respect, we herein aimed to investigate the amount of HBL and identify its possible risk factors.Methods: We enrolled 59 patients with SIS who received shoulder arthroscopy between December 2019 and June 2020 in this study. The clinical data recorded included the height of patients, weight pre- and postoperative hematocrit (Hct), which were used to calculate HBL using Gross’s formula. We analyzed the risk factors, including sex, age, BMI (body mass index), stage of SIS, diabetes, hypertension, and operative time using multivariate linear regression analysis.Results: Our results revealed that the mean of HBL was 341.4 ± 214.9 mL, while that of the postoperative Hb loss was 13.3 ± 8.0 g/L. The incidence of postoperative anemia was significantly associated with HBL (χ2 = 14.496, P < 0.001). Furthermore, multivariate linear regression analysis demonstrated that all seven factors, including gender (P = 0.698), age (P = 0.553), BMI (P = 0.854), stage of SIS (P = 0.906), diabetes (P = 0.984), hypertension (P = 0.532), and operative time (P = 0.645), were not significantly associated with HBL. Conclusion: Findings from this study show that postoperative HBL following shoulder arthroscopy was significant, which can aggravate anemia or lead to secondary anemia, thus should not be neglected.

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Surgery for rotator cuff tears

Cited by 67 publications

References 103 publications

PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews

PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews

Synergistic enhancement of tendon-to-bone healing via anti-inflammatory and pro-differentiation effects caused by sustained release of Mg²⁺/curcumin from injectable self-healing hydrogels

Hidden Blood Loss and Factors in Shoulder Arthroscopy Surgery: A Review of 59 Patients

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Surgery for rotator cuff tears

Cited by 67 publications

References 103 publications

PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews

PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews

Synergistic enhancement of tendon-to-bone healing via anti-inflammatory and pro-differentiation effects caused by sustained release of Mg2+/curcumin from injectable self-healing hydrogels

Hidden Blood Loss and Factors in Shoulder Arthroscopy Surgery: A Review of 59 Patients

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Synergistic enhancement of tendon-to-bone healing via anti-inflammatory and pro-differentiation effects caused by sustained release of Mg²⁺/curcumin from injectable self-healing hydrogels