Surgery Is an Art, Live Yours in Colors: Specimen Color Coding in Head and Neck Oncology

Vatsyayan, Ashutosh; Patel, Pankaj Kumar; Mandlik, Dushyant; Patel, Kaustubh

doi:10.1007/s13193-019-00941-6

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…Vatsyayan A (2019) 12 , Criswell (2021) 13 , Mardiana AA (2019) 14 are of the same view regarding the usefulness of poster colours in marking of surgical specimen. Mardiana AA (2019) conducted his study in Malaysia and used poster colours which is a cheaper version of acrylic paints and found it to be a reliable alternate to India ink and strongly recommended its use in routine histopathology.…”

Section: Discussionmentioning

confidence: 97%

Comparative Benefits of Tissue Marking by Poster Ink in Histopathology

Sarwar

Tanwni

Usman

et al. 2022

J Islamabad Med Dental Coll

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Background: Tissue margin marking with India ink is important in decision making for surgeons. The present study was conducted to examine the reliability of different shades of locally available poster colours in tissue marking and to evaluate the colour perceptibility microscopically in comparison with similar tissues marked by India ink. Methodology: This experimental study was conducted at Department of Pathology, HBS Medical & Dental College & Hospital, Islamabad from 27th February 2021 to 29th April 2021. Sample size was fifty, collected through convenient sampling technique. Five types of formalin fixed tissue specimens were selected for the study so as to evaluate the effectiveness of poster ink marking on different tissue surfaces. From each specimen, four sections were taken from the margins. Three shades of poster colour (black, blue and green) were used to ink three sections while one section from each tissue type was marked with India ink. After complete tissue processing and routine haematoxylin and eosin (H&E) staining, slides were examined microscopically. Scoring was done on a scale 0 to 3 on the basis of visibility. Results: The present study showed that poster colours inking of the tissues was quite reliable as compared to India ink. Most consistent results were achieved with black and blue colours as compared to green colour. Conclusion: Poster colours are reliable tool for tissue marking when India ink is not available. Their availability in a variety of colours provides them an edge over India ink. Key words: Eosin, India ink, Resection Margins

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Section: Discussionmentioning

confidence: 97%

Comparative Benefits of Tissue Marking by Poster Ink in Histopathology

Sarwar

Tanwni

Usman

et al. 2022

J Islamabad Med Dental Coll

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Oncological Outcome Following 3-Drug Neo-Adjuvant Chemotherapy Initiated “Triple Regimen” for Selected Subset of cT4b Bucco-Alveolar Carcinoma with Supra-Notch Infratemporal Fossa Extension

Patel,

Mandlik,

Gupta

et al. 2023

Journal of Head &Amp; Neck Physicians and Surgeons

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Background: Locally advanced bucco-alveolar complex carcinoma (T4b) with supra-notch (supra-sigmoid notch) infratemporal fossa (ITF) extension is an oncological challenge with poor outcome. We analyzed oncological outcome in patients managed with 3-drug neo-adjuvant chemotherapy (NACT) followed with surgical compartmental resection and adjuvant radiotherapy/Chemotherapy-RT (RT/CTRT), i.e., “Triple regimen.” Materials and Methods: Thirty-three cases of T4b bucco-alveolar complex carcinoma with supra-notch ITF extension were included from June 2009 to January 2017. Patients received 3-Drug NACT for 2–3 cycles every 21 days. Response to NACT was assessed with clinical examination, improvement in symptoms (like improved mouth opening etc.,), and Response Evaluation Criteria in Solid Tumors (RECIST) criterion. Patients showing stable disease and responders on NACT underwent compartmental surgical resection with complete ITF clearance followed by adjuvant RT/CTRT. Data were analyzed using STATA 13 and Kaplan − Meir graphs for survival rates. Results: Thirty-one patients (93.9%) showed response on NACT and subsequently went ahead with surgery. Clinical response according to RECIST criterion and subjective clinical improvement of more than 50% was noted in 18 cases while it was <50% in 13 cases. Seventeen of the 31 patients were disease free at last follow-up. There were no recurrences in ITF. The 3-year disease-free survival and disease-specific survival were 69% and 73%, respectively. Conclusion: Three-drug NACT followed by surgical resection in selected cases who show response to NACT with adjuvant chemoradiation provides a realm of hope for these borderline resectable T4b supra-notch cases.

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Surgery Is an Art, Live Yours in Colors: Specimen Color Coding in Head and Neck Oncology

Cited by 2 publications

References 4 publications

Comparative Benefits of Tissue Marking by Poster Ink in Histopathology

Comparative Benefits of Tissue Marking by Poster Ink in Histopathology

Oncological Outcome Following 3-Drug Neo-Adjuvant Chemotherapy Initiated “Triple Regimen” for Selected Subset of cT4b Bucco-Alveolar Carcinoma with Supra-Notch Infratemporal Fossa Extension

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