Surgical Antibiotic Prophylaxis in Children Undergoing Surgery: A Systematic Review and Meta-Analysis

Nthumba, Peter; Huang, Yongxu; Perdikis, Galen; Kranzer, Katharina

doi:10.1089/sur.2022.131

Cited by 3 publications

(3 citation statements)

References 89 publications

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“…Picón et al, (2022), refieren que antes de la cirugía, el sitio de la incisión debe desinfectarse con un antiséptico para eliminar cualquier contaminación. El objetivo de la profilaxis es atacar la flora nociva presente en la piel, es por ello, que se considera eficaz realizarla en el perioperatorio para evitar cualquier infección durante el procedimiento (Beaton et al,2022;Nthumba et al, 2022).…”

Section: Resultsunclassified

Revisión bibliográfica: Infección de herida quirúrgica: profilaxis y tratamiento

Chicaiza¹,

Guaita²,

Ocaña³

et al. 2023

LATAM

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La infección post quirúrgica en el sitio de incisión, se manifiesta por la aparición de una serie de microorganismos como staphilococcus aureus, enterococos, escherichia coli, entre otros. Es por ello, que el tratamiento dependerá de la magnitud de infección y del antibiograma, basándose en una terapia antimicrobiana sensible y de amplio espectro, mientras que la profilaxis antibiótica dependerá del tipo de cirugía y sitio quirúrgico a ser intervenido, es por ello que la presente investigación tuvo como objetivo conocer el tratamiento y profilaxis de infección de herida quirúrgica, mediante una revisión bibliográfica de tipo no experimental descriptivo, comparando diferentes investigaciones científicas, en donde se concluyó que la infección de herida quirúrgica es una de las complicaciones que se presenta con mayor frecuencia en las unidades operativas, que dependen de factores endógenos y exógenos, por ende, es necesario utilizar profilaxis antibiótica, y en caso de existir infección usar el antibiótico adecuado según los signos clínicos que se identifique en el paciente.

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Section: Resultsunclassified

Revisión bibliográfica: Infección de herida quirúrgica: profilaxis y tratamiento

Chicaiza¹,

Guaita²,

Ocaña³

et al. 2023

LATAM

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“…This information will be epitome in order to reduce SSI as well as to enhance patient health. Nonetheless SAP is only a single portion to check SSI (Nthumba et al, 2022). This article will also show how SAP impose its impact with other precautions for example surgical sites antibiotics and glycemic controls go enhance patient results.…”

Section: Introductionmentioning

confidence: 95%

Antibiotic prophylaxis for preventing surgical site infections after abdominal surgery

Hanfi,

Ahmad,

Singh

et al. 2024

ijhs

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Surgical site infections (SSIs) pose severe burden in healthcare, specially in laparoscopic surgeries. It,s the leading cause of morbidity, mortality, and healthcare costs. The reason to improve this strategy is to enhance SAP practices for laparoscopic surgery by evaluating different antibiotics prophylaxis. Conducting a thorough examination on the basis of vast studies results in effective SAP implications to rule out laparoscopic surgeries leading to reduce SSI effort and safety of patient. Our research put great significance on customized approaches to SAP. In addition to SAP,various factors such as the kind of procedure, patient-specific risks, antimicrobial resistance and other preventive measures,such as surgical site antiseptics and glycemic control, RCS is also important in preventing SSIs. In addition to SAP, surgical techniques, postoperative care, and stewardship after administration outside the operative suite are needed. High-quality studies in diverse populations and development of standardized SAP protocols are warranted to optimize patient outcomes. To sum up this discussion , this chronological review gives esteemed awareness into improving SAP procedures for laparoscopic surgery. By amalgamating evidence-based guidelines and promoting effective antibiotic management , physicians and surgeons can contribute to reducing SSIs and ameliorate patient safety worldwide.

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“…Surgical prophylaxis emerged as prevalent in our surveys (107 prescriptions, or 30.4% of all prophylactic indications), with amoxicillin and clavulanate, gentamicin, and cefuroxime as the most frequently prescribed agents for this purpose. Prophylaxis exceeding 24 h generally does not yield improved clinical outcomes and should therefore be avoided to mitigate adverse drug events and the development of antimicrobial resistance [19][20][21]. More insights on the challenges in capability, opportunity, and motivation to prescribe prophylaxis for longer than necessary would be helpful in improving prescribing behaviour.…”

Section: Meropenem Reservementioning

confidence: 99%

Trends in Antibiotic Use in a Large Children’s Hospital in London (United Kingdom): 5 Years of Point Prevalence Surveys

Meesters,

Chappell,

Demirjian

2024

Antibiotics

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Background: Antibiotics are commonly prescribed in paediatrics. As their excessive use contributes to adverse drug events, increased healthcare costs, and antimicrobial resistance, antimicrobial stewardship initiatives are essential to optimising medical care. These single-centre point prevalence surveys aimed to provide insights into antibiotic prescribing trends and identify targets for paediatric AMS activities. Methods: 14 point prevalence surveys were conducted from March 2016–April 2021, collecting data on antibiotic prescriptions, indication, adherence to guidelines, and route of administration. The UK adapted the World Health Organisation’s AWaRe classification-guided antibiotic categorization. Results: 32.5% of all inpatients were on at least one antimicrobial; this remained stable during all surveys (range: 20–44%, p = 0.448). Of all prescriptions, 67.2% had an end- or review-date, and the majority was for agents in the Watch category (46.8–70.5%). Amoxicillin and clavulanate were the most frequently prescribed antibiotics (20.8%), followed by gentamicin (15.3%). Approximately 28.8% of all prescriptions were for prophylactic indications, while 7.6% of the prescriptions were not adherent to the hospital guidelines. Conclusions: This study highlights the importance of ongoing monitoring and robust AMS initiatives to ensure prudent antibiotic prescribing in paediatric healthcare. It underscores the need for tailored guidelines, educational efforts, and targeted interventions to enhance the quality of antibiotic usage, ultimately benefiting both individual patients and public health.

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Surgical Antibiotic Prophylaxis in Children Undergoing Surgery: A Systematic Review and Meta-Analysis

Cited by 3 publications

References 89 publications

Revisión bibliográfica: Infección de herida quirúrgica: profilaxis y tratamiento

Revisión bibliográfica: Infección de herida quirúrgica: profilaxis y tratamiento

Antibiotic prophylaxis for preventing surgical site infections after abdominal surgery

Trends in Antibiotic Use in a Large Children’s Hospital in London (United Kingdom): 5 Years of Point Prevalence Surveys

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