Surgical Approaches Based on Biological Objectives: GTR versus GBR Techniques

Pellegrini, G; Pagni, Giorgio; Rasperini, Giulio

doi:10.1155/2013/521547

Cited by 41 publications

(37 citation statements)

References 130 publications

(137 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The bone graft was used as a scaffold for clot stabilization and cellular infiltration, according to the principles of GTR when associated with bone grafting. 24 Accordingly, the tooth root needed to be isolated to attempt to prevent root ankylosis. Even the processes involved in new bone regeneration cannot lead to new attachment formation.…”

Section: Discussionmentioning

confidence: 99%

How do GTR and GBR Differ? A Periodontitis Case Treated Using an Equine-derived, Enzyme-deantigenic, Collagenpreserving Bone Graft, and Collagen Membranes

Tizzoni¹,

Tizzoni²

2019

The Journal of Contemporary Dental Practice

View full text Add to dashboard Cite

Aim:The present case illustrates how a tooth, which had a highly questionable prognosis, was preserved by carrying out a periodontal regeneration surgery. Background: Treatment of periodontitis involves a careful consideration of all the factors that may allow the achievement of a favorable outcome; among those, the skillful use of guided tissue regeneration (GTR) membranes is of paramount importance. Case description: A 39-year-old patient presented with a mobile central upper incisor due to severe periodontitis and was treated according to GTR principles using a collagen membrane. A collagen-preserving bone graft was also used, as a scaffold for clot formation and cellular infiltration, which was covered with a second collagen membrane. The patient was contacted for follow-up assessment at 3, 6, 12, and 18 months after surgery. Follow-up radiographs showed that bone regeneration occurred around the involved tooth and very little tooth mobility was observed. The patient's masticatory function, appearance, and comfort were favorable. Conclusion: The use of two equine collagen membranes with the purpose of creating the best conditions to carry out periodontal regeneration according to GTR principles, in association with an equine, collagen-preserving, enzyme-deantigenic bone graft, allowed sufficient bone regeneration to salvage a tooth that was deemed otherwise lost because of periodontitis. Clinical significance: In cases of teeth that are severely compromised by periodontitis, the use of collagen membranes according to GTR principles can allow the regeneration of the periodontal tissues; the association with a bone substitute having well-known performance rates, covered with a collagen membrane (guided bone regeneration, GBR) can, in some cases, improve bone regeneration at the defect site.

show abstract

Section: Discussionmentioning

confidence: 99%

How do GTR and GBR Differ? A Periodontitis Case Treated Using an Equine-derived, Enzyme-deantigenic, Collagenpreserving Bone Graft, and Collagen Membranes

Tizzoni¹,

Tizzoni²

2019

The Journal of Contemporary Dental Practice

View full text Add to dashboard Cite

show abstract

“…7,19,21 Various techniques have been described to overcome these limits, including the free gingival graft, the interposition of connective-periosteal tissue, a scroll palatal flap positioned coronally, a flap of palatal advancement, a palatal flap rotated, and a lingual flap with coronal advancement. 6,8,22 The flap design, according to our prescription, seems to be a viable alternative to reduce tissue tension and hence, the risk of dehiscence during the healing time in the GBR procedures. We made a full-thickness incision at the base of the alveolar ridge similar to that described in the past by Buser et al 23,24 Hur et al 5 gave the hypotheses that the periosteal and the mucous layer maintain their own vascularization following their separation.…”

Section: Discussionmentioning

confidence: 99%

Use of a Partial-thickness Flap for Guided Bone Regeneration in the Upper Jaw

Porcaro

Busa

Bianco

et al. 2017

The Journal of Contemporary Dental Practice

View full text Add to dashboard Cite

Introduction: Guided bone regeneration (GBR) aims to restore adequate bone volume for the placement of implants in an ideal location.In this article, we analyze different surgical techniques for tissue management during GBR and a modified partialthickness surgical approach. Materials and methods:In a year's time span, five patients were enrolled in the study: Four women and one man (aged 44-59 years). In four patients, a GBR with simultaneous implant placement was adopted, whereas in another patient, a delayed implant placement was done. The flap was of full thickness and overturned on the side palatal with the aim of a retractor, thus exposing the bone crest. The graft material was covered and protected with a resorbable collagen membrane (Geistlich BioGide ® , Switzerland). The periosteal layer of the flap was then positioned above the resorbable membrane without traction. The sutures as vertical mattress were then positioned. Each patient received an intramuscular betamethasone dose (4 mg/50 kg) and antibiotic therapy for 7 days (amoxicillin + clavulanic acid 1 gm every 12 hours) and was instructed to maintain oral hygiene and appropriate wound cleaning. The patients were recalled at different times to monitor the healing. Results:No cases of tissue dehiscence were observed during the period of wound healing. One patient, however, showed a delayed exposure 4 months after surgery. This occurrence was managed without complications for the patient. Conclusion:The design of proposed flap seems to be effective in controlling the risk of dehiscence during the healing time in the GBR. The vascular supply was rarely compromised. The results we obtained are encouraging even if further studies on this technique are needed. Clinical significance: Lateral partial-thickness flaps seem to be effective in controlling tissue tension and consequently the risk of dehiscence. The incision vestibularly performed should favor the soft tissue healing. Use of a Partial-thickness Flap for Guided Bone

show abstract

“…The barrier membrane allows space for the supporting tissue of the bone to be regenerated [7]. The membrane also prevents soft tissue invasion to the area to be regenerated [8]. Clinical results of guided tissue regeneration using bone graft and membrane are shown in Figure 1.…”

Section: Guided Tissue Regenerationmentioning

confidence: 99%

Clinical Application of Enamel Matrix Derivative for Periodontal Regeneration and Treatment of Peri-Implantitis

Park¹

2019

Periodontology and Dental Implantology

View full text Add to dashboard Cite

One of the goals of periodontal therapy is to regenerate lost supporting structures that have been destroyed by periodontal disease. Treatment procedures including various bone grafts, guided tissue regeneration, use of enamel matrix derivative, or combinations of the aforementioned have been suggested as regenerative periodontal therapies to achieve this goal. Enamel matrix derivative is composed of a number of proteins, 90% of which are amelogenins, and these proteins are thought to induce the formation of periodontal attachment during tooth formation. Previous reports have shown that enamel matrix derivative was able to improve clinical attachment level and reduce probing depth. The results of previous controlled clinical trials have shown that using enamel matrix derivative in combination with bovine porous bone mineral may enhance the regenerative outcome with regard to the clinical attachment level gain compared with using the enamel matrix derivative alone. In this chapter, an extensive review of the role of enamel matrix derivate will be performed using in vitro and in vivo studies. Clinical implications of the enamel matrix derivative will also be discussed.

show abstract

Surgical Approaches Based on Biological Objectives: GTR versus GBR Techniques

Cited by 41 publications

References 130 publications

How do GTR and GBR Differ? A Periodontitis Case Treated Using an Equine-derived, Enzyme-deantigenic, Collagenpreserving Bone Graft, and Collagen Membranes

How do GTR and GBR Differ? A Periodontitis Case Treated Using an Equine-derived, Enzyme-deantigenic, Collagenpreserving Bone Graft, and Collagen Membranes

Use of a Partial-thickness Flap for Guided Bone Regeneration in the Upper Jaw

Clinical Application of Enamel Matrix Derivative for Periodontal Regeneration and Treatment of Peri-Implantitis

Contact Info

Product

Resources

About