Surgical Aspects of Pancreas Transplantation

Benedetti, Enrico; Sileri, Pierpaolo; Kandaswamy, Raja; Gruessner, Rainer W.G.; Beebe, David S.; Belani, Kumar G.

doi:10.1007/978-1-4757-4371-5_8

Cited by 4 publications

(1 citation statement)

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“…Understanding the factors for early losses and hence reduction of technical failure, late complications related to chronic immunosuppression also gained importance in attempting maintenance of pancreatic function lasting. Currently, nearly all the transplants simultaneous pancreas/kidney described in the literatures are induced with depleting or non-depleting drugs, hence the incidence of graft loss due to immune pancreatic the first year post-transplant decreased to 2.6% [13,22,23].…”

Section: Discussionmentioning

confidence: 99%

Death Receptor in the First Year after Simultaneous Pancreas/Kidney Transplantation

Sousa¹

2014

J Nephrol Ther

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Background: Simultaneous pancreas/kidney transplants require a long graft survival and recipient with to achieve more benefits than risks. In order to access the risk for this procedure, we evaluate the risk factors of death receptor with one year postoperatively in 292 simultaneous pancreas/kidney transplants evaluated 22 variables. Materials and Methods: Twenty-two variables were selected for the study, nine from receivers, eight from donors and five variables related to the surgical procedure. To determine the survival of patients, we evaluated dates of transplants, the latest consultation and dates of deaths. All independent variables were compared with the dependent variable: patient lost in a year. Those with statistical significance through univariate analyzes, were also analyzed by multiple logistic regression technique in an attempt to develop a mathematical model capable of predicting 1-year patient loss. Results: Relatively to the loss of patient in one year, the multivariate analysis identified body mass index receptor (p ≤ 0.008) and induction therapy (negative factor p ≤ 0.008) as independent risk factors. Conclusion: Based on the results of this research can be concluded that the independent variables related to one year loss of receptor are: body mass index of the donor and induction therapy.

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Section: Discussionmentioning

confidence: 99%