Surgical Biopsy of Suspected Interstitial Lung Disease Is Superior to Radiographic Diagnosis

Assessing the Safety and Clinical Impact of Thoracoscopic Lung Biopsy in Patients with Interstitial Lung Disease

“…There was no non-surgical cohort for comparison. The cohort of patients in this study was small but in agreement with similar studies of larger cohorts [12]. Though all patients who had a surgical lung biopsy were included, we do not know the total number of patients evaluated for ILD in this time period.…”

Surgical lung biopsy for differential diagnosis of interstitial lung disease

“…In the last few years, two studies consisting 224 and 194 patients concluded that the number of biopsies has no effect on reaching a specific diagnosis and taking less biopsies was defended since less inflammation and less injury would be provided in lung parenchyma. [20,23] In the present study, the number of biopsies was mostly decided during the procedure and the number of biopsies did not make a significant difference on diagnostic yield.…”

“…[5][6][7]18,20,21] In the published series, the diagnostic yield of SLB ranged between 34 to 98% and the most common diagnosis was reported as IPF. [19,20] In the current study, final diagnosis was reached in 80% and the most common diagnosis was UIP, which complies with the existing literature. Also, diagnoses of sarcoidosis and tuberculosis were reached in 12.4% and 4%, respectively, while malignancy was diagnosed in 5% of the patients.…”

“…[5,19,20] The most frequent complication has been described as prolonged air leak. [6,19] In our study, mortality rate was 2%, and rates of major and minor complications were 1.5% and 9.5%, respectively.…”

“…Blackhall et al [6] 103 Median 2 biopsy in -Taking at least 2 biopsy is suggested patients with specifically diagnosed Kayatta et al [20] 194 >1 in 100% -Biopsy site and number of the patients do not effect diagnosis rate…”