Surgical bladder preserving strategies in the treatment of muscle-invasive bladder cancer

Kuczyk, Markus A.; Machtens, S.; Bokemeyer, Carsten; Kollmannsberger, Christian; Hartmann, Jakob; Kondoh, Masao; Merseburger, Axel S.; Jonas, Udo

doi:10.1007/s00345-002-0278-z

Cited by 10 publications

(2 citation statements)

References 51 publications

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“… 1 Critics of PC also argued that the tumor recurrence rate after PC was relatively high, which ranged from 19% to 58%, and two-thirds of tumor recurrence appeared during the first 2 years. 5 As a result, one important component of bladder sparing treatment modality was vigilant surveillance after surgery, because early detection of tumor recurrence resulted in excellent outcome of salvage radical cystectomy. 6 However, the window to salvage cystectomy was short, and the disease carried a poor prognosis once patients developed extravesical disease caused by delayed diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Deceptive Muscle Invasive Bladder Cancer Recurrence With Benign Biopsy Foci After Bladder Sparing Treatment

Zeng

Zhang

et al. 2015

Medicine

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Most of recurrent bladder carcinoma after partial cystectomy did not cause diagnostic difficulties for urologists, because of the appearance of typical papillary in ultrasonography or cystoscopy, and could be easily confirmed by tumor biopsy. Three patients, ages from 35 to 62 years, had undergone bladder sparing treatment for muscle invasive bladder cancer, all of them had biopsy revealed benign bladder lesion at surveillance cystoscopy. However, transurethral resection of bladder tumor showed high-grade muscle invasive urothelial bladder carcinoma for these patients. Two patients were thus delayed for timely cystectomy and consequently resulted in local or distal metastasis.As a result, we recommended that timely pelvic enhanced computed tomography and transurethral resection of bladder tumor were necessary when bladder lesion occurred after partial cystectomy, avoiding the possibility of missing muscle invasive urothelial bladder carcinoma recurrence and delaying timely cystectomy.

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Section: Discussionmentioning

confidence: 99%

Deceptive Muscle Invasive Bladder Cancer Recurrence With Benign Biopsy Foci After Bladder Sparing Treatment

Zeng

Zhang

et al. 2015

Medicine

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“…In a review of the literature, Kuczyk et al . reported a local recurrence after partial cystectomy varying between 38% and 78% after partial cystectomy, based on available literature [8]. Herr et al .…”

Section: Purposementioning

confidence: 99%

Bladder preservation with brachytherapy compared to cystectomy for T1-T3 muscle-invasive bladder cancer: a systematic review

Bos¹,

Marmolejo²,

Rasch³

et al. 2014

jcb

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PurposeRadical cystectomy currently is the treatment of choice in muscle-invasive bladder cancer. However, cystectomy is associated with considerable morbidity. Bladder sparing treatment consists of transurethral resection of the tumor (with or without partial cystectomy), external beam radiotherapy, and brachytherapy. The purpose of this study is to compare bladder preservation with brachytherapy to cystectomy by a systematic review.Material and methodsA systematic review was conducted using PubMed electronic database. Article selection was done independently by two authors. Data were extracted on cause-specific survival and overall survival at 2, 5, and 10 years. Comparison of the two treatment modalities was done by a Weibull survival analysis with metaregression analysis and estimation of Hazard Ratio's (HR's) with 95% confidence intervals (CI).ResultsLarge differences in tumor staging and tumor grading were found between cystectomy and bladder sparing series. The adjusted HR's for cause-specific survival and overall survival were 1.27 (95% CI: 1.15-1.40) and 0.85 (95% CI: 0.84-0.87), respectively for bladder sparing relative to radical cystectomy.ConclusionsRobustness of the analysis is hampered by the retrospective character of the study and differences in patient characteristics. For selected cases, bladder sparing by brachytherapy leads to at least similar overall survival compared to radical cystectomy for muscle invasive bladder cancer.

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Bladder Cancer

et al. 2011

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Surgical bladder preserving strategies in the treatment of muscle-invasive bladder cancer

Cited by 10 publications

References 51 publications

Deceptive Muscle Invasive Bladder Cancer Recurrence With Benign Biopsy Foci After Bladder Sparing Treatment

Deceptive Muscle Invasive Bladder Cancer Recurrence With Benign Biopsy Foci After Bladder Sparing Treatment

Bladder preservation with brachytherapy compared to cystectomy for T1-T3 muscle-invasive bladder cancer: a systematic review

Bladder Cancer

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