Surgical complications after simultaneous pancreas–kidney transplantation: A single-center experience

Khubutia, Mogely Shalvovich; Пинчук, А. В.; Дмитриев, И. В.; Балкаров, А. Г.; Сторожев, Р. В.; Anisimov, Yu. A.

doi:10.1016/j.asjsur.2015.11.003

Cited by 24 publications

(20 citation statements)

References 7 publications

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“…In our daily practice, we have observed that patients who have undergone SPKT, even when they have experienced major postoperative complications , and, in some cases, lost one or both grafts, still wish to be put on the waiting list for re‐transplantation. We have questioned, for example, what factors would lead to a patient's desire to be put on the waiting list again, despite the great psychological and physical suffering involved, including the risk of serious complications and even possible death given the initial unsuccessful transplant.…”

Section: Discussionmentioning

confidence: 99%

The quality of life in type I diabetic patients with end‐stage kidney disease before and after simultaneous pancreas‐kidney transplantation: a single‐center prospective study

et al. 2019

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Summary Simultaneous pancreas‐kidney transplantation (SPKT) aimed at increasing the life expectancy for diabetic patients with end‐stage kidney disease (ESKD). However, the risks of surgery complications and immunosuppression therapy make it unclear if the SPKT positively impacts patient's quality of life (QoL). Using the Kidney Disease Quality of Life—Short‐Form Health Survey (KDQOL‐SF36) and Problems Areas in Diabetes (PAID) measurement tools, we compared the QoL of 57 patients on the pretransplant waiting list with that of 103 patients who had undergone SPKT. Posttransplantation patients were assessed within different time intervals (<1, 1–3, and >3 years). Mean KDQOL‐SF36 scores were better among posttransplantation patients in the SF36 and KDQOL domains. It was also observed patients’ stress reduction in PAID mean score (P = 0.011) after SPKT. We concluded that patients receiving SPKT had a better perception of QoL than did patients on the waiting list, and this positive perception remained almost entirely comparable over the three different intervals of the posttransplantation time. These positive results showed better outcomes when excluding patients that lost pancreas graft function. Further research is needed to compare diabetic patients with kidney transplant alone using specific measurement tools to evaluate patient's QoL.

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Section: Discussionmentioning

confidence: 99%

The quality of life in type I diabetic patients with end‐stage kidney disease before and after simultaneous pancreas‐kidney transplantation: a single‐center prospective study

et al. 2019

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“…Generally the pancreas and kidney are transplanted with an intraperitoneal approach into contralateral iliac fossae . There is evidence that of the routinely performed solid organ transplants, pancreas transplantation has the highest rate of complications . This is likely a result of the exocrine secretions of the pancreas as well as its low microcirculatory blood flow …”

Section: Discussionmentioning

confidence: 99%

An audit of pregnancy outcomes in solid organ transplant recipients at a metropolitan hospital

Fang

Nayyar

Diplock

2018

Aust NZ J Obst Gynaeco

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“…Pancreas transplantation is known to confer high patient morbidity and mortality, often leading to complications with a prolonged hospital stay. The median length of stay after transplant varies by centre but has been reported in the range of 8-27 days [14,15], with some studies putting the postoperative complication rate at close to 40% with reoperation rates exceeding 30% [16,17]. The patients themselves are also known to be high risk, with virtually all patients have diabetes mellitus, and many of these patients have concomitant cardiovascular or renal disease.…”

Section: Why Is An Eras Pathway So Important For Pancreatic Transplantation?mentioning

confidence: 99%

Working towards an ERAS Protocol for Pancreatic Transplantation: A Narrative Review

Elango

Papalois

2021

JCM

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Enhanced recovery after surgery (ERAS) initially started in the early 2000s as a series of protocols to improve the perioperative care of surgical patients. They aimed to increase patient satisfaction while reducing postoperative complications and postoperative length of stay. Despite these protocols being widely adopted in many fields of surgery, they are yet to be adopted in pancreatic transplantation: a high-risk surgery with often prolonged length of postoperative stay and high rate of complications. We have analysed the literature in pancreatic and transplantation surgery to identify the necessary preoperative, intra-operative and postoperative components of an ERAS pathway in pancreas transplantation.

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Surgical complications after simultaneous pancreas–kidney transplantation: A single-center experience

Abstract: We conclude that the high rate of surgical complications is a major obstacle to widespread application of pancreas transplantation; early recognition and appropriate treatment of graft-related complications is fundamental for graft survival.

Cited by 24 publications

References 7 publications

The quality of life in type I diabetic patients with end‐stage kidney disease before and after simultaneous pancreas‐kidney transplantation: a single‐center prospective study

The quality of life in type I diabetic patients with end‐stage kidney disease before and after simultaneous pancreas‐kidney transplantation: a single‐center prospective study

An audit of pregnancy outcomes in solid organ transplant recipients at a metropolitan hospital

Working towards an ERAS Protocol for Pancreatic Transplantation: A Narrative Review

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