Surgical Complications and Evolution of Grafts in Children with Renal Transplantation at Cayetano Heredia National Hospital

Abstract

Objective: This study aims to determine surgical complications and graft outcome in children undergoing renal transplantation at Cayetano Heredia National Hospital (CHNH). Materials and Methods: A case study series focused on the incidence of surgical complications and graft outcome in pediatric patients with end stage renal disease (ESRD) who underwent renal transplant (RT) between December 2007 and March 2011. Results: The study described 29 pediatric transplant patients whose average age was 13.69 ± 3.38 (6.2 -17.9) years. The etiology of end stage renal disease (ESRD) was renal hypoplasia in 12 patients (41.38%), primary glomerulopathy in 10 patients (34.48%), obstructive uropathy in 4 patients (13.79%), vasculitis in 2 patients (6.9%) and hemolytic uremic syndrome (HUS) in 1 (3.45%) patient. There were 11 surgical complications (34.48%): 2 cases of arterial thrombosis, 3 cases of urinary fistula, 3 of lymphocele, 1 of venous thrombosis, urinoma and perineal collection. The follow-up time was 15.84 ± 12.19 months. Graft survival at 12, 24, and 40 months was 89.29%, 77.16% and 77.16%, respectively. Conclusion: Surgical complications and graft survival in pediatric renal transplantation in our series did not differ from other published series.

Peritonitis Rate in Children on Chronic Peritoneal Dialysis Impact on Survival

“…RRT needs to be started in children when the GFR drops below 30ml/min/1.73 m 2 , i.e., at stage 4 or 5 [7].RRT includes renal transplantation, hemodialysis (HD), and PD. Although renal transplantation is the most commonly used modality, peritoneal dialysis is effective and it is a suitablwe option for achieving proper metabolic and nutritional control [8][9][10]. In recent years, 70% of the pediatric patients in the United States has been treated with PD, and approximately 60% in Europe and 93% in Japan [11].There are two types of chronic PD modalities: Continuous Ambulatory Peritoneal Dialysis (CAPD) and Automated Peritoneal Dialysis (APD) [12,13].Peritoneal dialysis in pediatric patients can lead to infectious complications, such as peritonitis.…”

“…RRT includes renal transplantation, hemodialysis (HD), and PD. Although renal transplantation is the most commonly used modality, peritoneal dialysis is effective and it is a suitablwe option for achieving proper metabolic and nutritional control [8][9][10]. In recent years, 70% of the pediatric patients in the United States has been treated with PD, and approximately 60% in Europe and 93% in Japan [11].…”