“…23 Some experts suggest the use of prophylactic antibiotics if the child has VUR, immunosuppression, partial urinary tract obstruction, recurrent UTIs with normal renal function, two episodes of UTIs within 6 months, or 3 episodes within 12 months, as in our patient. 18,24,25 In a 2011 metaanalysis, the long-term use of prophylactic antibiotics did not significantly reduce the number of recurrent UTIs, but was able to decrease the risk of new kidney damage, with number needed to treat (NNT) of 33 in 2-3 years. 26 The prognosis in congenital obstructive conditions depends on compliance to therapy, renal function before and after correction of the obstruction, age at diagnosis, the presence of VUR at the time of diagnosis, accompanying UTIs, proteinuria, hypertension and the initial therapy given to the patient.…”