2016
DOI: 10.1002/jso.24442
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Surgical excision margin for primary acral melanoma

Abstract: Thin AM were successfully treated with a 1 cm excision margin. For thick AM, a 2 cm excision margin provided improved local control, compared with a <2 cm margin; however, this benefit did not translate into a survival gain. J. Surg. Oncol. 2016;114:933-939. © 2016 Wiley Periodicals, Inc.

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Cited by 16 publications
(7 citation statements)
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“…Moreover, our data indirectly allude to more favourable results obtained via MMS than in previous studies. 9,18 The 5-year OS and DFS rates (78% and 76%, respectively) after SLNB without blue dye use were similar to or higher than those reported from Asian countries in general or from studies of patients who underwent classical SLNB, 30,33,34 but were lower than the rates obtained in previous studies similar to ours. 7,8 This may be attributed to the proportion of patients with ALM, and a mean Breslow thickness that was much higher in our study than in the others.…”
Section: Discussionsupporting
confidence: 85%
“…Moreover, our data indirectly allude to more favourable results obtained via MMS than in previous studies. 9,18 The 5-year OS and DFS rates (78% and 76%, respectively) after SLNB without blue dye use were similar to or higher than those reported from Asian countries in general or from studies of patients who underwent classical SLNB, 30,33,34 but were lower than the rates obtained in previous studies similar to ours. 7,8 This may be attributed to the proportion of patients with ALM, and a mean Breslow thickness that was much higher in our study than in the others.…”
Section: Discussionsupporting
confidence: 85%
“…Postoperative complications may include hematoma, wound infection, thromboembolism, flap loss, and in exceptional cases, progression to amputation. 2 …”
Section: Discussionmentioning
confidence: 99%
“…Clinical margins required for thick acral lentiginous melanoma often lead to wide surgical excisions that cause a tremendous impact on quality of life and function. 1 , 2 The repair of large, full-thickness defects on the plantar surface of young patients may become a reconstructive challenge.…”
Section: Introductionmentioning
confidence: 99%
“…The treatment of choice is complete surgical excision. In the case of thick ALM, a safety margin of 2 cm is recommended to decrease the risk of local recurrence, while disease-free survival and melanoma-specific survival were not improved [ 13 ]. To achieve a complete tumour resection amputation is not always preventable – as shown in our patient [ 2 ].…”
Section: Discussionmentioning
confidence: 99%